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Cancer: Lymphoma
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Total 590 results found since Jan 2013.
Scales of Magt1 Gene: Novel Mutations, Different Presentations
Iran J Allergy Asthma Immunol. 2022 Feb 6;21(1):92-97. doi: 10.18502/ijaai.v21i1.8622.ABSTRACTLoss-of-function mutations in magnesium transporter 1 (MAGT1) gene cause X-linked magnesium deficiency with Epstein-Barr virus (EBV) infection and neoplasm (X-MEN), a disease with quite diverse clinical and immunological consequences. The phenotypic characteristics of the initially described patients included CD4+ T cell lymphopenia, immune deficiency, EBV viremia, and EBV-related lymphoproliferative disease. To date, a total of 25 patients have been reported. The spectrum of the MAGT1 defect ranges from other viral infections (HS...
Source: Iranian Journal of Allergy, Asthma and Immunology - May 7, 2022 Category: Allergy & Immunology Authors: Sule Haskologlu Kubra Baskin Caner Aytekin Candan Islamoglu Serdar Ceylaner Figen Dogu Nurdan Tacyildiz Emel Unal Aydan Ikinciogullari Source Type: research
Relationship between low serum IgE levels and malignancies in 9/11 World Trade Center responders
CONCLUSION: WTC-responders with low serum IgE levels had the highest odds of developing hematologic malignancies. This hypothesis-generating study suggests that low serum IgE levels might be associated with the development of specific malignancies in at-risk individuals exposed to carcinogens. Larger, multicenter studies with adequate follow up of individuals with different IgE levels are needed to better evaluate this relationship.PMID:35872243 | DOI:10.1016/j.anai.2022.07.012
Source: Annals of Allergy, Asthma and Immunology - July 25, 2022 Category: Allergy & Immunology Authors: Denisa Ferastraoaru Rachel Zeig-Owens David G Goldfarb Alexandra K Mueller Charles B Hall Michael D Weiden Theresa Schwartz David J Prezant David Rosenstreich Source Type: research
Elevated Interleukin-10 Levels Are Associated with Low Platelet Count and Poor Prognosis in 90 Adult Patients with Hemophagocytic Lymphohistiocytosis
Conclusion: Infection and lymphoma are the leading causes of HLH in adult patients with heterogeneous clinical manifestations. Survival of adult HLH is frustrating, especially those associated with malignancies. Besides, elevated IL-10 levels were associated with lower platelet counts, and these two markers were independent risk factors for poor prognosis. Earlier treatment led to better outcomes.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - January 12, 2023 Category: Allergy & Immunology Source Type: research
New Presentation of CD27 Deficiency; Coronary Ectasia and COVID-19
Iran J Allergy Asthma Immunol. 2023 Feb 20;22(1):110-118. doi: 10.18502/ijaai.v22i1.12013.ABSTRACTCD27 is a costimulatory receptor involved in the maturation of the innate and adaptive immunity. CD27, through interaction with CD70, plays a role in the control of Epstein-Barr virus (EBV) infection. CD27 deficiency leads to an immune dysregulation disease characterized by EBV susceptibility. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might put patients with primary immunodeficiency at risk for adverse outcomes. Chromogenic in situ hybridization (CISH) study was performed to detect EBV in the lymphoma tissue...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2023 Category: Allergy & Immunology Authors: Zahra Golchehre Samin Sharafian Nader Momtazmanesh Zahra Chavoshzadeh Abdollah Karimi Hassan Abolhassani Maryam Kazemi Aghdam Koroush Vahidshahi Seyedehatefeh Hashemimoghaddam Farid Kosari Zahra Khafafpour Bibi Shahin Shamsian Mohammad Keramatipour Source Type: research
