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Cancer: Lymphoma
Infectious Disease: COVID-19
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Total 84 results found since Jan 2013.
Frequency of HLA-DR+CD38hi T cells identifies and quantifies T-cell activation in hemophagocytic lymphohistiocytosis, hyperinflammation, and immune regulatory disorders
Evaluation of T-cell activation is essential for the diagnosis of numerous hyperinflammatory and immune regulatory disorders, including hemophagocytic lymphohistiocytosis (HLH).1-6 Currently, plasma levels of soluble IL-2 receptor (sIL-2R) or sCD25/ αchain of the IL-2R complex are extensively used as a biomarker for measuring T-cell activation.7 Its role in the assessment of disease severity and monitoring has been established in a spectrum of hyperinflammatory disorders (HLH, multisystem inflammatory syndrome in children [MIS-C]),4,8,9 autoim mune disorders,10 infections (eg, HIV, EBV, coronavirus disease 2019 [COVID-19]...
Source: Journal of Allergy and Clinical Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Thinh H. Nguyen, Deepak Kumar, Chengyu Prince, Dylan Martini, Jocelyn R. Grunwell, Taylor Lawrence, Trenton Whitely, Karin Chappelle, Satheesh Chonat, Sampath Prahalad, Michael Briones, Shanmuganathan Chandrakasan Source Type: research
New Presentation of CD27 Deficiency; Coronary Ectasia and COVID-19
Iran J Allergy Asthma Immunol. 2023 Feb 20;22(1):110-118. doi: 10.18502/ijaai.v22i1.12013.ABSTRACTCD27 is a costimulatory receptor involved in the maturation of the innate and adaptive immunity. CD27, through interaction with CD70, plays a role in the control of Epstein-Barr virus (EBV) infection. CD27 deficiency leads to an immune dysregulation disease characterized by EBV susceptibility. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might put patients with primary immunodeficiency at risk for adverse outcomes. Chromogenic in situ hybridization (CISH) study was performed to detect EBV in the lymphoma tissue...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2023 Category: Allergy & Immunology Authors: Zahra Golchehre Samin Sharafian Nader Momtazmanesh Zahra Chavoshzadeh Abdollah Karimi Hassan Abolhassani Maryam Kazemi Aghdam Koroush Vahidshahi Seyedehatefeh Hashemimoghaddam Farid Kosari Zahra Khafafpour Bibi Shahin Shamsian Mohammad Keramatipour Source Type: research
