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Cancer: Leukemia

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Total 693 results found since Jan 2013.

M101 the effect of bruton tyrosine kinase inhibitor ibrutinib on diagnostic evaluation amoxicillin allergy
Bruton Tyrosine Kinase (BTK) Inhibitors are used to treat chronic lymphocytic leukemia. BTK is involved in B cell receptor signaling and downstream signaling in mast cell and basophils. The BTK inhibitor Ibrutinib may block mast cell and basophil mediator release and may affect IgE levels.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: R. Charya, D. Sheth, A. Aggarwal Source Type: research

Atypical features of cutaneous adverse drug reactions during therapy for hairy cell leukemia.
Publication date: Available online 15 June 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Julie Castagna, Emmanuelle Amsler, Flore Kurihara, François Chasset, Annick Barbaud, Angèle Soria
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 17, 2020 Category: Allergy & Immunology Source Type: research

Atypical features of cutaneous adverse drug reactions during therapy for hairy cell leukemia
Publication date: October 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 9Author(s): Julie Castagna, Emmanuelle Amsler, Flore Kurihara, François Chasset, Annick Barbaud, Angèle Soria
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 7, 2020 Category: Allergy & Immunology Source Type: research

Oridonin Could Inhibit Inflammation and T-cell Immunoglobulin and Mucin-3/Galectin-9 (TIM-3/Gal-9) Autocrine Loop in the Acute Myeloid Leukemia Cell Line (U937) as Compared to Doxorubicin
In this study, we evaluated the effects of oridonin and doxorubicin on the TIM-3/Gal-9 autocrine loop. We also evaluated oridonin anti-inflammatory and anti-cancer properties on U937 cells, as an AML cell line in comparison to doxorubicin as a common anthracycline drug for AML treatment. Cell counting kit-8 (CCK-8) was applied to evaluate the cytotoxicity of oridonin and doxorubicin on U937 cells and also to determine the impact of galectin-9 (Gal-9) on their proliferation. The effects of oridonin and doxorubicin on Gal-9, TIM-3, and interleukin-1β (IL-1β) gene expression were determined by real-time polymerase chain rea...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Farzad Nasri Fatemeh Sadeghi Nafiseh Behranvand Azam Samei Mohammad Reza Bolouri Tahereh Azari Elaheh Abdollahi Foad Ghazizadeh Manijeh Motevalian Zuhair Mohammad Hassan Reza Falak Source Type: research

Leukemia Inhibitory Factor Suppresses NKG2D mRNA Expression and Presentation on Human Natural Killer Cells
This study aimed to evaluate the effect of LIF on natural killer group 2 member D (NKG2D) receptors' expression and presentation on natural killer (NK) cells. For this purpose, peripheral blood mononuclear cells taken from 4 young male healthy blood donors were isolated and the effect of LIF (25 ng/mL) after 12, 24, and 48 hours of incubation, on NKG2D receptors expression and presentation was investigated using flow cytometry and real-time-polymerase chain reaction (PCR). All of the steps of the experiment were performed in duplicate. After periods of 12, 24, and 48 hours, LIF reduced both the expression and presentation ...
Source: Iranian Journal of Allergy, Asthma and Immunology - February 27, 2021 Category: Allergy & Immunology Authors: Zahra Abdoli Mohammad-Ali Assarehzadegan Mohammad Hassan Pipelzadeh Sara Iranparast Nader Dashti Gerdabi Mehdi Parsanahad Ali Khodadadi Source Type: research

Oridonin Could Inhibit Inflammation and T-cell Immunoglobulin and Mucin-3/Galectin-9 (TIM-3/Gal-9) Autocrine Loop in the Acute Myeloid Leukemia Cell Line (U937) as Compared to Doxorubicin
In this study, we evaluated the effects of oridonin and doxorubicin on the TIM-3/Gal-9 autocrine loop. We also evaluated oridonin anti-inflammatory and anti-cancer properties on U937 cells, as an AML cell line in comparison to doxorubicin as a common anthracycline drug for AML treatment. Cell counting kit-8 (CCK-8) was applied to evaluate the cytotoxicity of oridonin and doxorubicin on U937 cells and also to determine the impact of galectin-9 (Gal-9) on their proliferation. The effects of oridonin and doxorubicin on Gal-9, TIM-3, and interleukin-1β (IL-1β) gene expression were determined by real-time polymerase chain rea...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Farzad Nasri Fatemeh Sadeghi Nafiseh Behranvand Azam Samei Mohammad Reza Bolouri Tahereh Azari Elaheh Abdollahi Foad Ghazizadeh Manijeh Motevalian Zuhair Mohammad Hassan Reza Falak Source Type: research

Leukemia Inhibitory Factor Suppresses NKG2D mRNA Expression and Presentation on Human Natural Killer Cells
This study aimed to evaluate the effect of LIF on natural killer group 2 member D (NKG2D) receptors' expression and presentation on natural killer (NK) cells. For this purpose, peripheral blood mononuclear cells taken from 4 young male healthy blood donors were isolated and the effect of LIF (25 ng/mL) after 12, 24, and 48 hours of incubation, on NKG2D receptors expression and presentation was investigated using flow cytometry and real-time-polymerase chain reaction (PCR). All of the steps of the experiment were performed in duplicate. After periods of 12, 24, and 48 hours, LIF reduced both the expression and presentation ...
Source: Iranian Journal of Allergy, Asthma and Immunology - February 27, 2021 Category: Allergy & Immunology Authors: Zahra Abdoli Mohammad-Ali Assarehzadegan Mohammad Hassan Pipelzadeh Sara Iranparast Nader Dashti Gerdabi Mehdi Parsanahad Ali Khodadadi Source Type: research