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Cancer: Leukemia
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Total 724 results found since Jan 2013.
Novel BCL-2 Inhibitor Lisaftoclax in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematologic Malignancies: First-in-Human Open-Label Trial
CONCLUSIONS: Lisaftoclax was well tolerated, with no evidence of tumor lysis syndrome. Dose-limiting toxicity was not reached at the highest dose level. Lisaftoclax has a unique pharmacokinetic profile compatible with a potentially more convenient daily (vs. weekly) dose ramp-up schedule and induced rapid clinical responses in patients with CLL/SLL, warranting continued clinical investigation.PMID:37074726 | DOI:10.1158/1078-0432.CCR-22-3321
Source: Clinical Cancer Research - April 19, 2023 Category: Cancer & Oncology Authors: Sikander Ailawadhi Zi Chen Bo Huang Aneel Paulus Mary C Collins Lei Tommy Fu Mingyu Li Mohammad Ahmad Lichuang Men Hengbang Wang Matthew S Davids Eric Liang Divya J Mekala Zhicong He Masa Lasica Costas K Yannakou Ricardo Parrondo Laura Glass Dajun Yang As Source Type: research
Intrathecal CAR-NK cells infusion for isolated CNS relapse after allogeneic stem cell transplantation: case report
In conclusion, IT CAR-NK cells infusion is a potentially feasible and effective option for patients with CNS relapse, with limited neurological toxicity.PMID:36941630 | DOI:10.1186/s13287-023-03272-0
Source: Cell Research - March 21, 2023 Category: Cytology Authors: Jing Yuan Fuxu Wang Hanyun Ren Source Type: research
CML-127 Results of a Vaccination Against COVID-19 by a Vector Based Vaccine Sputnik V in Patients With Chronic Myeloid Leukemia
CONCLUSIONS: Sputnik V vaccine showed no unexpected or severe AEs in CML patients. Seroconversion rate of about 93-94% was close to the 3-phase trial data (94-97%). No strong age-dependent/time-dependent correlation of antibody levels was found in the tested time period. Sputnik V vaccination is safe and acceptable in CML patients.PMID:36163909 | DOI:10.1016/S2152-2650(22)01364-7
Source: Herpes - September 27, 2022 Category: Infectious Diseases Authors: Ekaterina Chelysheva Anna Petrova Margarita Gurianova Oleg Shukhov Anastasia Bykova Irina Nemchenko Dmitry Tikhomirov Hunan Julhakyan Alina Kokhno Anna Turkina Source Type: research
Orbital and intracranial metastasis secondary to thyroid carcinoma
CONCLUSIONS: In these cases, the surgical treatment is essential to improve patient's symptoms and quality of life.PMID:34762636 | DOI:10.24875/CIRU.20001274
Source: Cirugia y Cirujanos - November 11, 2021 Category: Surgery Authors: Jos é F Sánchez-Sánchez Yazmin Lemus-Rodr íguez Ricardo Ram írez-Aguilar Andr és A Briseño-Hernández Marcela Ramos-Barrales Source Type: research
