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Prevalence of Primary Liver Cancer is Affected by Place of Birth in Hispanic People Residing in the United States: All of Us Research Program Report
DISCUSSION: This is the first report using All of Us data to show that non-US born Hispanic participants have a higher risk of liver cancer compared to US born participants. Further analyses, including genomic studies, are necessary to understand these differences and identify targets for risk reduction interventions.PMID:35854430 | DOI:10.1177/00031348221109465
Source: The American Surgeon - July 20, 2022 Category: Surgery Authors: Jingjing Yu Brittany G Sullivan Girish N Senthil Amber Gonda Farideh Dehkordi-Vakil Belinda Campos Farshid Dayyani Maheswari Senthil Source Type: research

Precancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine: an analysis of the long-term follow-up study from the randomised Costa Rica HPV Vaccine Trial
Lancet Oncol. 2022 Jun 13:S1470-2045(22)00291-1. doi: 10.1016/S1470-2045(22)00291-1. Online ahead of print.ABSTRACTBACKGROUND: In women vaccinated against human papillomavirus (HPV), reductions in cervical disease and related procedures results in more women having intact transformation zones, potentially increasing the risk of cervical lesions caused by non-vaccine-preventable HPV types, a phenomenon termed clinical unmasking. We aimed to evaluate HPV vaccine efficacy against cervical intraepithelial neoplasia grade 2 or worse (CIN2+) and cervical intraepithelial neoplasia grade 3 or worse (CIN3+) attributed to non-preven...
Source: Cancer Control - June 16, 2022 Category: Cancer & Oncology Authors: Jaimie Z Shing Shangying Hu Rolando Herrero Allan Hildesheim Carolina Porras Joshua N Sampson John Schussler John T Schiller Douglas R Lowy M ónica S Sierra Loretto Carvajal Aim ée R Kreimer Costa Rica HPV Vaccine Trial Group Source Type: research

Effectiveness of an mHealth intervention to increase adherence to triage of HPV DNA positive women who have performed self-collection (the ATICA study): A hybrid type I cluster randomised effectiveness-implementation trial
Lancet Reg Health Am. 2022 May;9:100199. doi: 10.1016/j.lana.2022.100199. Epub 2022 Feb 13.ABSTRACTBACKGROUND: Human Papillomavirus (HPV) self-collection offered by community health workers (CHWs) during home visits has been hampered by low levels of triage Pap among HPV-positive women. We investigated effectiveness of a mHealth intervention to increase adherence to triage Pap.METHODS: We conducted a hybrid type I cluster randomised effectiveness-implementation trial in Jujuy, Argentina. CHWs (clusters) were eligible if actively offering HPV self-collection and served at least 26 women aged 30 years and over. Women were el...
Source: Cancer Control - June 3, 2022 Category: Cancer & Oncology Authors: Silvina Arrossi Melisa Paolino Victoria S ánchez Antelo Laura Thouyaret Racquel E Kohler Milca Cuberli Liliana Flores Ver ónica Serra Kasisomayajula Viswanath Liliana Orellana ATICA Study team Source Type: research

Janssen Presents Study Results Showing Clinical Efficacy for TREMFYA ® (guselkumab) and Long-Term Safety Profile for STELARA® (ustekinumab) for Patients Living with Inflammatory Bowel Disease at Digestive Disease Week® 2022
SPRING HOUSE, PENNSYLVANIA, May 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 2 GALAXI 1 clinical trial of TREMFYA® (guselkumab) in adult patients with moderately to severely active Crohn’s disease (CD), and from three separate long-term pooled analyses of adult patients with ulcerative colitis (UC) and CD treated with STELARA® (ustekinumab).1,2,3,4 These data are being presented as oral and poster presentations and are among 29 Janssen abstracts presented during the Digestive Disease Week® (DDW) meeting taking place in person and virtually in San Di...
Source: Johnson and Johnson - May 24, 2022 Category: Pharmaceuticals Source Type: news

AI recognition of patient race in medical imaging: a modelling study
Lancet Digit Health. 2022 May 11:S2589-7500(22)00063-2. doi: 10.1016/S2589-7500(22)00063-2. Online ahead of print.ABSTRACTBACKGROUND: Previous studies in medical imaging have shown disparate abilities of artificial intelligence (AI) to detect a person's race, yet there is no known correlation for race on medical imaging that would be obvious to human experts when interpreting the images. We aimed to conduct a comprehensive evaluation of the ability of AI to recognise a patient's racial identity from medical images.METHODS: Using private (Emory CXR, Emory Chest CT, Emory Cervical Spine, and Emory Mammogram) and public (MIMI...
Source: Cancer Control - May 14, 2022 Category: Cancer & Oncology Authors: Judy Wawira Gichoya Imon Banerjee Ananth Reddy Bhimireddy John L Burns Leo Anthony Celi Li-Ching Chen Ramon Correa Natalie Dullerud Marzyeh Ghassemi Shih-Cheng Huang Po-Chih Kuo Matthew P Lungren Lyle J Palmer Brandon J Price Saptarshi Purkayastha Ayis T Source Type: research

Fight Aging! Newsletter, October 18th 2021
In this study, we therefore analysed the influence of lithium treatment on lifespan and parameters of health during ageing in mice. To determine the concentration of lithium suitable to be administered in a longitudinal ageing study, we first tested the effects of lithium chloride (LiCl) in doses from 0.01 to 2.79 g LiCl per kg chow. C57Bl/6J mice fed with 1.05-2.79 g/kg LiCL in the diet showed lithium plasma levels between 0.4 and 0.8 mM/l. While plasma levels to 0.4 and 0.8 mM/l are well tolerated by human patients, at doses above 1.44 g LiCl/kg, we observed an obvious dose-dependent polydipsia combined with a dis...
Source: Fight Aging! - October 17, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace. No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news

He ’s the First African American to Receive a Face Transplant. His Story Could Change Health Care
Robert Chelsea turned down the first face he was offered. It was a fine face, one that could have taken him off the transplant waiting list after just a couple months. But Chelsea—severely disfigured after a catastrophic car accident five years earlier—was in no hurry. He’d gotten used to tilting his head back so food and water wouldn’t fall out of his nearly lipless mouth. He knew how to respond compassionately to children who stared in shock and fear. The face, offered in May 2018, had belonged to a man with skin that was much fairer than what remained of Chelsea’s—so light that Chelse...
Source: TIME: Health - October 24, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Healthcare Source Type: news

Virtual #CochraneSantiago - Meet our content creators!
Cochrane ’s first virtual Colloquium is happening 2-6 December, 2019. Cochrane ’s Colloquium is an annual, global health event based on promoting the most prestigious evidence in the world and where hundreds of international researchers, opinion leaders, health experts and patients join together for open, scientific debate promoting the use of evidence in health. Through act ivities and presentations, we will be exploring this year ' s theme of “Embracing diversity”.Meet our content creator volunteers who will be helping to share the work of Cochrane and our virtual#CochraneSantiagomaterials and discussion to their...
Source: Cochrane News and Events - October 7, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

The Top 10 Trends Shaping the Future of Pharma
The drug sends a message to a caregiver after the patient swallowed it. The doctor prescribes virtual reality treatments for migraines. Do you think it is science fiction? You are mistaken. Just let me familiarize you with the top 10 trends shaping the future of pharma. I gave a speech recently to an audience of professionals working in healthcare regulation for the invitation of the Consumer Healthcare Products Association in Washington. After the keynote, a guy raised his hand and asked me the following: how can a regulatory agency keep up with the speed of new technologies in pharma? I get a lot of questions like this o...
Source: The Medical Futurist - June 20, 2017 Category: Information Technology Authors: nora Tags: Future of Medicine Future of Pharma 3d printing artificial intelligence augmented reality digital health gc4 Innovation nanotechnology Personalized medicine pharmacies pharmacogenetics pharmacology virtual reality VR Source Type: blogs