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Infectious Disease: Hepatitis B
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Total 97 results found since Jan 2013.
When two viruses collide: coronavirus disease after hepatitis B virus reactivation
We report a fatal case of metastatic colorectal cancer survivor who developed COVID-19 after clinically reactivated hepatitis B virus (HBV) due to chemotherapy. The patient's COVID-19 illness was supposed to be related to her recent medical evaluation. Although being diagnosed with chronic HBV infection for decades, she was not treated with nucleotide analogue and the possibility to preclude HBV reactivation was missed. Moreover, infectious control practices must be draconian in order to save such a fragile population from infections.PMID:37144323 | DOI:10.3897/folmed.65.e79869
Source: Cancer Control - May 5, 2023 Category: Cancer & Oncology Authors: Radka T Komitova Ani Kevorkyan Petur Vasilev Elitsa Golgocheva-Markova Maria Atanasova Source Type: research
Circulating Sex Hormone Levels and Risk of Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Prospective Studies
CONCLUSIONS: Circulating levels of sex hormone-binding globulin and testosterone may influence the risk of gastric, liver, and colorectal cancer.IMPACT: Further clarifying the role of sex hormones in the development of gastrointestinal cancer may unravel future novel targets for prevention and treatment.PMID:37104672 | DOI:10.1158/1055-9965.EPI-23-0039
Source: Cancer Control - April 27, 2023 Category: Cancer & Oncology Authors: Zhiqiang Liu Yingfan Zhang Jesper Lagergren Shanshan Li Jingru Li Zhixian Zhou Zhijian Hu Shao-Hua Xie Source Type: research
Human Proteome Microarray identifies autoantibodies to tumor-associated antigens as serological biomarkers for the diagnosis of hepatocellular carcinoma
In conclusion, the panel of 6 TAAbs can provide potential value for HCC detection, and the strategy to identify novel serological biomarkers can also provide new clues in understanding immunodiagnostic biomarkers.PMID:36587394 | DOI:10.1002/1878-0261.13371
Source: Cancer Control - January 1, 2023 Category: Cancer & Oncology Authors: Qian Yang Hua Ye Guiying Sun Keyan Wang Liping Dai Cuipeng Qiu Jianxiang Shi Jicun Zhu Xiao Wang Peng Wang Source Type: research
Results of Novel Clinical Study of Guselkumab and Golimumab Combination Therapy Show Adults with Moderately to Severely Active Ulcerative Colitis Maintained Higher Rates of Clinical, Histologic, and Endoscopic Remission at Week 38
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from an ongoing analysis of a Phase 2a clinical trial showing adults with moderately to severely active ulcerative colitis (UC) who received 12 weeks of combination induction therapy with guselkumab and golimumab, followed by a transition to guselkumab alone for maintenance, achieved a clinical remission ratea (based on the modified Mayo score [mMayo])b at week 38 of 47.9 percent, a higher rate than induction and maintenance treatment with either guselkumab alone (31.0 percent) or golimumab al...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news
Expression Levels and Clinical Significance of Serum miR-497, CEA, CA24-2, and HBsAg in Patients with Colorectal Cancer
In conclusion, combined detection could diagnose CRC more accurately. Serum miR-497, CEA, and CA24-2 were important in the diagnosis of lymph node metastasis of CRC. HBsAg did a better job of predicting liver metastases in CRC patients. High level of CEA significantly reduced the cumulative survival rate of CRC patients and could predict the long-term survival rate of patients. Serum levels of miR-497, CEA, CA24-2, and HBsAg played a positive role in the diagnosis and evaluation of CRC and could identify lymph node and liver metastases, having a high clinical guidance value.PMID:35993056 | PMC:PMC9388305 | DOI:10.1155/2022/3541403
Source: Biomed Res - August 22, 2022 Category: Research Authors: Yan Liu Jie Chen Source Type: research
Incidence, Mortality Features and Lifetime Risk Estimation of Digestive Tract Cancers in an Urban District of Shanghai, China
This study aimed to describe the burden, recent trends and lifetime risks in the incidence and mortality of digestive tract cancers in an urban district of Shanghai, China. Our study extracted data on stomach, colon, rectum and liver cancers diagnosed in Changning District between 2010 and 2019 from the Shanghai Cancer Registry. We calculated age-standardized incidence and mortality rates, the risks of developing and dying from cancer, and the estimated annual percent changes. Between 2010 and 2019, 8619 new cases and 5775 deaths were registered with digestive tract cancers in the district. The age-standardized incidence r...
Source: Cancer Control - June 25, 2022 Category: Cancer & Oncology Authors: Jing-Hao Bi Hui-Yun Yuan Yu Jiang Yun Zhang Wen-Wei Zheng Lei Zhang Zhuo-Ying Li Hong-Lan Li Yu-Ting Tan Wen-Sui Zhao Yong-Bing Xiang Source Type: research
All-Cause and Cause-Specific Mortality in Middle-Aged Individuals with Positive HBsAg: Findings from a Prospective Cohort Study
CONCLUSION: HBV is associated with significant mortality risk from different causes in Iranian adults. However, solely focusing on liver outcomes in Iranian HBV patients might result in overlooking non-liver events, especially CVD and extrahepatic cancers.PMID:35429954 | DOI:10.34172/aim.2022.24
Source: Archives of Iranian Medicine - April 17, 2022 Category: Middle East Health Authors: Nazgol Motamed-Gorji Sareh Eghtesad Maryam Sharafkhah Sahar Masoudi Maryam Darvishian Layli Eslami Abdolsamad Gharavi Masoud Khoshnia Gholamreza Roshandel Amaneh Shayanrad Sanam Hariri Shahin Merat Hossein Poustchi Reza Malekzadeh Source Type: research
