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Condition: Obesity
Cancer: Colorectal Cancer
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Total 740 results found since Jan 2013.
Effects of obesity, and of weight loss following bariatric surgery, on methylation of DNA from the rectal mucosa and in cell-free DNA from blood
CONCLUSION: BS reversed LINE1, POMC and LEP methylation in the rectal mucosa of patients with obesity to levels similar to those in individuals without obesity. These findings support current evidence of effects of BS-induced weight loss on reversibility of DNA methylation in other tissues. The DNA methylation changes in the rectal mucosa shows promise as a biomarker for objective assessment of effects of weight loss interventions on risk of cancer and other diseases.PMID:37714902 | DOI:10.1038/s41366-023-01384-4
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Khalil ElGendy Fiona C Malcomson Sorena Afshar Michael D Bradburn John C Mathers Source Type: research
Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells
Cancer Metab. 2023 Sep 13;11(1):15. doi: 10.1186/s40170-023-00315-1.ABSTRACTHypercholesterolemia is often correlated with obesity which is considered a risk factor for various cancers. With the growing population of hypercholesterolemic individuals, there is a need to understand the role of increased circulatory cholesterol or dietary cholesterol intake towards cancer etiology and pathology. Recently, abnormality in the blood cholesterol level of colon cancer patients has been reported. In the present study, we demonstrate that alteration in cholesterol levels (through a high-cholesterol or high-fat diet) increases the inc...
Source: Cell Research - September 13, 2023 Category: Cytology Authors: Shyamananda Singh Mayengbam Abhijeet Singh Himanshi Yaduvanshi Firoz Khan Bhati Bhavana Deshmukh Dipti Athavale Pranay L Ramteke Manoj Kumar Bhat Source Type: research
Clinical features and surgical selection in colitis-associated colorectal cancer with ulcerative colitis
CONCLUSION: UC patients with cancer/dysplasia were more likely than refractory patients to have mild inflammation; they also had a longer duration of UC disease and better nutritional status.PMID:37641118 | PMC:PMC10463818 | DOI:10.1186/s12893-023-02160-x
Source: Hand Surgery - August 28, 2023 Category: Surgery Authors: Ryuichi Kuwahara Hiroki Ikeuchi Kurando Kusunoki Tomohiro Minagawa Yuki Horio Kei Kimura Kozo Kataoka Naohito Beppu Masataka Ikeda Motoi Uchino Source Type: research
Obesity and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):63-72. doi: 10.4166/kjg.2023.083.ABSTRACTThe prevalence of obesity has increased significantly worldwide, and this trend is likely to continue in the coming years. There is substantial evidence that obesity plays a crucial role in the development of colorectal cancer. Epidemiological data have consistently demonstrated a correlation between obesity and colorectal cancer. Insulin resistance, hyperinsulinemia, chronic inflammation, altered levels of growth factors, adipocytokines, and various hormones are plausible biological mechanisms. In addition, obesity has been shown to have an...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Jundeok Lee Su Young Kim Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
Obesity and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):63-72. doi: 10.4166/kjg.2023.083.ABSTRACTThe prevalence of obesity has increased significantly worldwide, and this trend is likely to continue in the coming years. There is substantial evidence that obesity plays a crucial role in the development of colorectal cancer. Epidemiological data have consistently demonstrated a correlation between obesity and colorectal cancer. Insulin resistance, hyperinsulinemia, chronic inflammation, altered levels of growth factors, adipocytokines, and various hormones are plausible biological mechanisms. In addition, obesity has been shown to have an...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Jundeok Lee Su Young Kim Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
Obesity and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):63-72. doi: 10.4166/kjg.2023.083.ABSTRACTThe prevalence of obesity has increased significantly worldwide, and this trend is likely to continue in the coming years. There is substantial evidence that obesity plays a crucial role in the development of colorectal cancer. Epidemiological data have consistently demonstrated a correlation between obesity and colorectal cancer. Insulin resistance, hyperinsulinemia, chronic inflammation, altered levels of growth factors, adipocytokines, and various hormones are plausible biological mechanisms. In addition, obesity has been shown to have an...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Jundeok Lee Su Young Kim Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
Obesity and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):63-72. doi: 10.4166/kjg.2023.083.ABSTRACTThe prevalence of obesity has increased significantly worldwide, and this trend is likely to continue in the coming years. There is substantial evidence that obesity plays a crucial role in the development of colorectal cancer. Epidemiological data have consistently demonstrated a correlation between obesity and colorectal cancer. Insulin resistance, hyperinsulinemia, chronic inflammation, altered levels of growth factors, adipocytokines, and various hormones are plausible biological mechanisms. In addition, obesity has been shown to have an...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Jundeok Lee Su Young Kim Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
Obesity and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):63-72. doi: 10.4166/kjg.2023.083.ABSTRACTThe prevalence of obesity has increased significantly worldwide, and this trend is likely to continue in the coming years. There is substantial evidence that obesity plays a crucial role in the development of colorectal cancer. Epidemiological data have consistently demonstrated a correlation between obesity and colorectal cancer. Insulin resistance, hyperinsulinemia, chronic inflammation, altered levels of growth factors, adipocytokines, and various hormones are plausible biological mechanisms. In addition, obesity has been shown to have an...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Jundeok Lee Su Young Kim Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
Obesity and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):63-72. doi: 10.4166/kjg.2023.083.ABSTRACTThe prevalence of obesity has increased significantly worldwide, and this trend is likely to continue in the coming years. There is substantial evidence that obesity plays a crucial role in the development of colorectal cancer. Epidemiological data have consistently demonstrated a correlation between obesity and colorectal cancer. Insulin resistance, hyperinsulinemia, chronic inflammation, altered levels of growth factors, adipocytokines, and various hormones are plausible biological mechanisms. In addition, obesity has been shown to have an...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Jundeok Lee Su Young Kim Source Type: research
Gut Microbiome and Colorectal Cancer
Korean J Gastroenterol. 2023 Aug 25;82(2):56-62. doi: 10.4166/kjg.2023.089.ABSTRACTColorectal cancer (CRC) is one of the most common cancers in Korea. A majority of CRCs are caused by progressive genomic alterations referred to as the adenoma-carcinoma sequence. The factors that may increase the risk of CRC include obesity and consumption of a high-fat diet, red meat, processed meat, and alcohol. Recently, the role of gut microbiota in the formation, progression and treatment of CRCs has been investigated in depth. An altered gut microbiota can drive carcinogenesis and cause the development of CRC. Studies have also shown ...
Source: Korean J Gastroenter... - August 25, 2023 Category: Gastroenterology Authors: Tae-Geun Gweon Source Type: research
