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Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives
Joseph D. Romano1,2,3,4 and Nicholas P. Tatonetti1,2,3,4*
1Department of Biomedical Informatics, Columbia University, New York, NY, United States
2Department of Systems Biology, Columbia University, New York, NY, United States
3Department of Medicine, Columbia University, New York, NY, United States
4Data Science Institute, Columbia University, New York, NY, United States
The discovery of new pharmaceutical drugs is one of the preeminent tasks—scientifically, economically, and socially—in biomedical research. Advances in informatics and computational biology have increased productivity at many ...
Source: Frontiers in Genetics - April 29, 2019 Category: Genetics & Stem Cells Source Type: research
Drought in the Semiarid Region of Brazil: Exposure, Vulnerabilities and Health Impacts from the Perspectives of Local Actors
Conclusion
The results obtained from this research shows, in general, the fragility in the social and political infrastructure necessary to improve the living conditions of populations, particularly those that depend on family agriculture in drought prone areas. The conditions of social, economic and environmental vulnerabilities presented in the region can be amplified by the drought process, and can aggravate the impacts resulting drought events, thus disadvantaging the population of this region, as shown in the Fig. 1.
The general perception of the interviewees of the health sector shows an agreement with what is found...
Source: PLOS Currents Disasters - October 29, 2018 Category: International Medicine & Public Health Authors: Aderita Sena Source Type: research
Nature Contact and Human Health: A Research Agenda
Conclusions:
Nature contact may offer a range of human health benefits. Although much evidence is already available, much remains unknown. A robust research effort, guided by a focus on key unanswered questions, has the potential to yield high-impact, consequential public health insights. https://doi.org/10.1289/EHP1663
Received: 26 January 2017
Revised: 12 May 2017
Accepted: 25 May 2017
Published: 31 July 2017
Address correspondence to H. Frumkin, Dept. of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Box 354695, Seattle, WA 98195-4695 USA; Telephone: 206-897-1723;...
Source: EHP Research - July 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
The Florence Statement on Triclosan and Triclocarban
Author Affiliations open
1Biodesign Center for Environmental Security, Arizona State University, Tempe, Arizona, USA
2Green Science Policy Institute, Berkeley, California, USA
3Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
4Environmental Working Group, Washington, District of Columbia, USA
5Department of Civil, Environmental, and Geo-Engineering, University of Minnesota, Minneapolis, Minnesota, USA
6Medical University of South Carolina, Department of Public Health Sciences, Charleston, South Carolina, USA
7Health Research Communicati...
Source: EHP Research - June 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research