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Pulmonary mucoepidermoid carcinoma in the Chinese population: A clinical characteristic and prognostic analysis
ConclusionThe clinical, radiographical and pathological features of pulmonary mucoepidermoid carcinoma were systemically analysed and summarized, and the degree of differentiation and lymph node metastasis, as well as prognostic factors in addition to clinical stage, were confirmed.
Source: Frontiers in Oncology - August 24, 2022 Category: Cancer & Oncology Source Type: research

Anticancer effects of Poncirus  fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion.
This study investigated the ability of PF to induce apoptosis and inhibit the invasiveness and migratory ability of HCC cell lines (Hep3B and Huh7). Wound healing, Transwell migration and invasion, and colony‑formation assays, as well as flow cytometry, were used to analyze cell proliferation, migration, invasion, and apoptosis. Epithelial‑mesenchymal transition (EMT)‑related and apoptotic proteins were assessed by western blotting. The mitochondrial membrane potential of the Hep3B and Huh7 cells was observed with tetramethylrhodamine ethyl ester. The reactive oxygen species (ROS) level was determined by dihydroethid...
Source: Oncology Reports - November 1, 2020 Category: Cancer & Oncology Tags: Oncol Rep Source Type: research

58P Risk factors for immune related adverse events: A retrospective study
ConclusionThis study helped distinguish potential risk factors for irAE, like the female gender and history of allergies. Autoimmune disorders are already reported as risk factores. However the small sample isn't enough for us to draw accurate conclusions. More prospective trials are waranted in this setting.Legal entity responsible for the studyThe authors.FundingHas not received any funding.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - December 15, 2019 Category: Cancer & Oncology Source Type: research

Allergies and Atopic Dermatitis in Relation to Skin Cancer
Conclusion: Our findings suggest that allergies and atopy may influence risk of early onset BCC and SCC, and that effects may be gender specific. Impact: A deeper understanding of the immune mechanisms underlying allergies and atopy may provide new routes of preventing keratinocyte cancers. Cancer Epidemiol Biomarkers Prev; 24(4); 749–54. ©2015 AACR.
Source: Cancer Epidemiology Biomarkers and Prevention - March 31, 2015 Category: Cancer & Oncology Authors: Cheng, J., Zens, M. S., Duell, E., Perry, A. E., Chapman, M. S., Karagas, M. R. Tags: Research Articles Source Type: research