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Cancer: Epithelial Cancer
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Total 1185 results found since Jan 2013.
Tanshinone I attenuates gastric precancerous lesions by inhibiting epithelial mesenchymal transition through the p38/STAT3 pathway
CONCLUSION: This study showed that Tan-I inhibited the progression of GPLs by reversing the EMT process and reducing inflammation by restraining the p38/STAT3 signaling pathway.PMID:37699302 | DOI:10.1016/j.intimp.2023.110902
Source: International Immunopharmacology - September 12, 2023 Category: Allergy & Immunology Authors: Dan Liang Shiyun Tang Lu Liu Maoyuan Zhao Xiao Ma Yanling Zhao Caifei Shen Qingsong Liu Jianyuan Tang Jinhao Zeng Nianzhi Chen Source Type: research
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research
Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research
Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research
Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research
Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research
Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research
