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Management: National Institutes of Health (NIH)
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Total 261 results found since Jan 2013.
Physical Activity Intervention Characteristics and Effects on Behavioral and Health-Related Outcomes Among Adolescents and Young Adults Living with and Beyond Cancer: A Systematic Review
J Adolesc Young Adult Oncol. 2023 Sep 8. doi: 10.1089/jayao.2023.0047. Online ahead of print.ABSTRACTParticipation in physical activity (PA) during and after cancer treatment is safe and beneficial in the adolescent and young adult (AYA) cancer population. PA can positively impact health-related outcomes; however, participation remains low. This systematic review aims to describe PA intervention characteristics and outcomes in AYA survivors of cancer (AYASCa). This review followed Preferred Reporting Index for Systematic Reviews and Meta Analyses (PRISMA) guidelines and was registered with Prospero (CRD42022365661). PubMed...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Rebecca L Hoover Jingle Xu Jamie L Conklin Hazel B Nichols Andrew Smitherman Carmina G Valle Todd Schwartz Deborah K Mayer Rachel Hirschey Source Type: research
The effect of butylphthalide on improving the neurological function of patients with acute anterior circulation cerebral infarction after mechanical thrombectomy
Medicine (Baltimore). 2023 Aug 25;102(34):e34616. doi: 10.1097/MD.0000000000034616.ABSTRACTButylphthalide can improve blood circulation in patients with acute cerebral infarction. Complement 3a receptor 1 (C3aR1) is involved in the regulation of innate immune response and pathogen monitoring, which is closely related to the pathophysiological processes of breast cancer, neurogenesis and lipid catabolism. Our study explored the therapeutic effect of butylphthalide on improving the neurological function of patients with acute anterior circulation cerebral infarction after mechanical thrombectomy, and evaluated the correlatio...
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Xinghua Wang Xinchi Luan Zhigang Yang Source Type: research
Family size for women with primary ovarian insufficiency and their relatives
Hum Reprod. 2023 Aug 25:dead168. doi: 10.1093/humrep/dead168. Online ahead of print.ABSTRACTSTUDY QUESTION: How does the number of children in women with primary ovarian insufficiency (POI) compare to the number for control women across their reproductive lifespans?SUMMARY ANSWER: Approximately 14% fewer women with POI will have children, but for those able to have children the median number is 1 less than for age-matched controls.WHAT IS KNOWN ALREADY: Women with POI are often identified when presenting for fertility treatment, but some women with POI already have children and there remains a low chance for pregnancy afte...
Source: Cancer Control - August 26, 2023 Category: Cancer & Oncology Authors: L E Verrilli K Allen-Brady E B Johnstone M A Alvord C K Welt Source Type: research
Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy model
EBioMedicine. 2023 Aug 14;95:104762. doi: 10.1016/j.ebiom.2023.104762. Online ahead of print.ABSTRACTBACKGROUND: Dolutegravir (DTG) is a recommended first-line regimen for all people with Human Immunodeficiency Virus (HIV) infection. Initial findings from Botswana, a country with no folate fortification program, showed an elevated prevalence of neural tube defects (NTDs) with peri-conceptional exposure to DTG. Here we explore whether a low folate diet influences the risk of DTG-associated foetal anomalies in a mouse model.METHODS: C57BL/6 mice fed a folate-deficient diet for 2 weeks, were mated and then randomly allocated ...
Source: Cancer Control - August 16, 2023 Category: Cancer & Oncology Authors: Haneesha Mohan Jessica Nguyen Ben MacKenzie Audrey Yee Evelyn Yukino Laurette Tanvi Sanghvi Oscar Tejada Valeriya Dontsova Kit-Yi Leung Cameron Goddard Taylor De Young John G Sled Nicholas D E Greene Andrew J Copp Lena Serghides Source Type: research
Revealing the concealed: A tribute to Donald L. Morton, MD
Clin Exp Metastasis. 2023 Jul 31. doi: 10.1007/s10585-023-10223-9. Online ahead of print.ABSTRACTDonald L. Morton, MD, epitomized one of America's dream scenarios: a person evolving from the humblest of origins to become an international celebrity in his profession, leading the world in the discipline of surgical oncology. His pioneering accomplishments in various roles have been well documented. Scientists, clinicians, students, and patients benefited from his contributions to the management of malignant diseases, particularly melanoma. His many attributes in pursuing the goal to cure malignant diseases are well known. Br...
Source: Clinical Breast Cancer - July 31, 2023 Category: Cancer & Oncology Authors: S David Nathanson Ian Wood Source Type: research
RNA-seq research landscape in Africa: systematic review reveals disparities and opportunities
AbstractRNA sequencing has emerged as the standard method for transcriptome profiling of several human diseases. We performed a systematic review detailing the state of RNA-seq analyses in Africa from its inception till February 2022. Our goal was to provide an update on the state of RNA-seq analyses in Africa, including research gaps, funding information, participants information, authorship and collaborations. Following the PRISMA guidelines, we performed an exhaustive literature search for RNA-seq studies conducted in Africa, using PubMed, Scopus and Academic Search Complete (EBSCOhost). The output was exported to Endno...
Source: European Journal of Medical Research - July 22, 2023 Category: Research Source Type: research
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial
Lancet. 2023 Jul 17:S0140-6736(23)01406-X. doi: 10.1016/S0140-6736(23)01406-X. Online ahead of print.ABSTRACTBACKGROUND: Hearing loss is associated with increased cognitive decline and incident dementia in older adults. We aimed to investigate whether a hearing intervention could reduce cognitive decline in cognitively healthy older adults with hearing loss.METHODS: The ACHIEVE study is a multicentre, parallel-group, unmasked, randomised controlled trial of adults aged 70-84 years with untreated hearing loss and without substantial cognitive impairment that took place at four community study sites across the USA. Participa...
Source: Cancer Control - July 21, 2023 Category: Cancer & Oncology Authors: Frank R Lin James R Pike Marilyn S Albert Michelle Arnold Sheila Burgard Theresa Chisolm David Couper Jennifer A Deal Adele M Goman Nancy W Glynn Theresa Gmelin Lisa Gravens-Mueller Kathleen M Hayden Alison R Huang David Knopman Christine M Mitchell Thoma Source Type: research
Psychedelics: Threshold of a Therapeutic Revolution
Neuropharmacology. 2023 May 27:109610. doi: 10.1016/j.neuropharm.2023.109610. Online ahead of print.ABSTRACTThis Special Issue of Neuropharmacology on psychedelics provides a timely and comprehensive update on progress following the previous Neuropharmacology Special Issue "Psychedelics: New Doors, Altered Perceptions". Remarkable advances have been made in basic and clinical research on psychedelics in the five years since 2018. It is partly based on the seminar series focused on psilocybin organized by the National Institutes of Health (NIH), USA from April to June 2021, the "NIH Psilocybin Research Speaker Series". Part...
Source: Neuropharmacology - May 29, 2023 Category: Drugs & Pharmacology Authors: D J Heal S L Smith S J Belouin J E Henningfield Source Type: research
