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Specialty: Cancer & Oncology
Cancer: Cancer
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Total 908 results found since Jan 2013.
Chronic cerebral hypoperfusion and blood-brain barrier disruption in uninjured brain areas of rhesus monkeys subjected to transient ischemic stroke
J Cereb Blood Flow Metab. 2022 Feb 9:271678X221078065. doi: 10.1177/0271678X221078065. Online ahead of print.ABSTRACTBlood-brain barrier (BBB) disruption is a pivotal pathophysiological process in ischemic stroke. Although temporal changes in BBB permeability during the acute phase have been widely studied, little is known about the chronic phase of cerebrovascular changes that may have a large impact on the long-term outcome. Therefore, this study was aimed to measure cerebral vascular abnormalities using CT perfusion in nine rhesus monkeys subjected to transient middle cerebral artery occlusion (tMCAO) for ≥1 year (MCA...
Source: Cancer Control - February 9, 2022 Category: Cancer & Oncology Authors: Yingqian Zhang Bangcheng Zhao Qi Lai Qinxi Li Xun Tang Yinbing Zhang Zhixiang Pan Qiang Gao Zhihui Zhong Source Type: research
Effectiveness of an individualized home-based physical activity program in surgery-free non-endarterectomized asymptomatic stroke patients: a study protocol for the PACAPh interventional randomized trial
This study has been approved by the National Ethics Committee (IDRCB:2019-A01543-54/SI:19.06.21.40640). ClinicalTrials.gov NCT04053166.PMID:35164816 | DOI:10.1186/s13063-022-06061-x
Source: Cancer Control - February 15, 2022 Category: Cancer & Oncology Authors: Mathilde Mura Emeraude Rivoire Leila Dehina-Khenniche Mich èle Weiss-Gayet B énédicte Chazaud Camille Faes Philippe Connes Anne Long Chantal L Rytz Pauline Mury Lidia Delrieu Etienne Gouraud Marine Bordet Nellie Della Schiava Patrick Lermusiaux Matthie Source Type: research
Atrial Fib, Elevated Lipids Raise Stroke Risk in Cancer Patients Atrial Fib, Elevated Lipids Raise Stroke Risk in Cancer Patients
New-onset or pre-existing AF predicted acute ischemic stroke or TIA in patients with cancer -- as did renal disease, dyslipidemia, and active cancer therapy -- in a case-control study.First Look
Source: Medscape Hematology-Oncology Headlines - February 24, 2022 Category: Cancer & Oncology Tags: Cardiology News Source Type: news
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016
Sci Rep. 2022 Feb 28;12(1):3252. doi: 10.1038/s41598-022-06074-1.ABSTRACTTo determine whether increasing thrombectomy-capable hospitals with moderate comprehensive stroke center (CSC) capabilities is a valid alternative to centralization of those with high CSC capabilities. This retrospective, nationwide, observational study used data from the J-ASPECT database linked to national emergency medical service (EMS) records, captured during 2013-2016. We compared the influence of mechanical thrombectomy (MT) use, the CSC score, and the total EMS response time on the modified Rankin Scale score at discharge among patients with a...
Source: Cancer Control - March 1, 2022 Category: Cancer & Oncology Authors: Ai Kurogi Daisuke Onozuka Akihito Hagihara Kunihiro Nishimura Akiko Kada Manabu Hasegawa Takahiro Higashi Takanari Kitazono Tsuyoshi Ohta Nobuyuki Sakai Hajime Arai Susumu Miyamoto Tetsuya Sakamoto Koji Iihara J-ASPECT Study Collaborators Source Type: research
Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration
The objectives of this study were to (1) determine the effect of MMP-12 suppression by shRNA-mediated gene silencing on neurological/functional recovery, (2) establish the optimal timing of MMP-12shRNA treatment that provides maximum therapeutic benefit, (3) compare the effectiveness of acute versus chronic MMP-12 suppression, and (4) evaluate potential sex-related differences in treatment outcomes. Young male and female Sprague-Dawley rats were subjected to transient middle cerebral artery occlusion and reperfusion. Cohorts of rats were administered either MMP-12shRNA or scrambled shRNA sequence (control) expressing plasm...
Source: Cancer Control - October 21, 2022 Category: Cancer & Oncology Authors: Siva Reddy Challa Koteswara Rao Nalamolu Casimir A Fornal Billy C Wang Ryan C Martin Elsa A Olson Ammar L Ujjainwala David M Pinson Jeffrey D Klopfenstein Krishna Kumar Veeravalli Source Type: research
Bioinformatic analysis and clinical diagnostic value of hsa_circ_0004099 in acute ischemic stroke
This study investigates the expression and effect of hsa_circ_0004099 in acute ischemic stroke (AIS). We conducted a case-controlled study that included 40 patients with AIS within 24 hours and 40 healthy subjects during the same period as a control group. Differentially expressed circular RNAs (circRNAs) were obtained using GEO2R, and the expression of hsa_circ_0004099 was verified using RT-PCR. Correlation analysis of the National Institutes of Health Stroke Scale (NIHSS) disease severity score and ischemic time with hsa_circ_0004099 expression levels was also performed. The receiver operating characteristic (ROC) curve ...
Source: Cancer Control - November 18, 2022 Category: Cancer & Oncology Authors: Jiqing Zheng Shuiming Luo Yaobin Long Source Type: research
Identification of ligustrazine-based analogs of piperlongumine as potential anti-ischemic stroke agents
Fitoterapia. 2022 Dec 20:105398. doi: 10.1016/j.fitote.2022.105398. Online ahead of print.ABSTRACTPiper longum has a specific aroma and spicy taste. In addition to edible value, current studies have shown that piper longum also has pharmacological activities such as anti-platelet aggregation, anti-inflammation, anti-cancer, anti-diabetes and anti-depression. Piperlongumine is an alkaloid isolated from Piper longum. Based on our previous studies, four Piperlongumine analogs were synthesized, and their anti-platelet aggregation activities were evaluated. Among them, compound 8 has the strongest anti-platelet aggregation acti...
Source: Cancer Control - December 23, 2022 Category: Cancer & Oncology Authors: Tan Lijuan Cao Xiaolu Wan Xin He Yuying Lan Xi Yang Xiliang Wang Ting Min Zhenli Zou Yu Source Type: research
Identification of cell death-related biomarkers and immune infiltration in ischemic stroke between male and female patients
CONCLUSION: These findings contribute to a better knowledge of immune cell infiltration and their corresponding molecular mechanisms of cell death and offer distinct clinically relevant biological targets for IS patients of different genders.PMID:37435058 | PMC:PMC10332266 | DOI:10.3389/fimmu.2023.1164742
Source: Cancer Control - July 12, 2023 Category: Cancer & Oncology Authors: Wenli Chen Yuanfang Chen Liting Wu Yue Gao Hangju Zhu Ye Li Xinyu Ji Ziyi Wang Wen Wang Lei Han Baoli Zhu Hongxing Wang Ming Xu Source Type: research
Brainstem discovered as important relay site after stroke
(University of Zurich) After a stroke, sufferers are often faced with the problem of severe movement impairment. Researchers at the Brain Research Institute of the University of Zurich have now discovered that the brainstem could play a major role in the recovery of motor functions. The projection of neurons from this ancient part of the brain into the spinal cord leads to the neural impulses needed for motion being rerouted.
Source: EurekAlert! - Cancer - February 25, 2014 Category: Cancer & Oncology Source Type: news
Study links severe sleep apnea to increased risk of stroke, cancer and death
(American Academy of Sleep Medicine) A new study shows that moderate to severe obstructive sleep apnea is independently associated with an increased risk of stroke, cancer and death.
Source: EurekAlert! - Cancer - April 14, 2014 Category: Cancer & Oncology Source Type: news
Glutamate imaging better than MR spectroscopy in first 3 hours after ischemic stroke
(American Roentgen Ray Society) Glutamate imaging reveals ischemic lesions in the first 3 hours after stroke that are not distinguishable in T1-weighted and T2-weighted imaging.
Source: EurekAlert! - Cancer - May 7, 2014 Category: Cancer & Oncology Source Type: news
Primary stroke prevention in Nigerian children with sickle cell disease (SPIN): Challenges of conducting a feasibility trial
ConclusionA hydroxyurea trial (NCT01801423) for children with SCD is feasible in sub‐Saharan Africa; however, extensive training and resources are needed to build a global patient oriented multi‐disciplinary research team with a common purpose. Pediatr Blood Cancer. © 2014 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - November 14, 2014 Category: Cancer & Oncology Authors: Najibah A. Galadanci, Shehu U. Abdullahi, Musa A. Tabari, Shehi Abubakar, Raymond Belonwu, Auwal Salihu, Kathleen Neville, Fenella Kirkham, Baba Inusa, Yu Shyr, Sharon Phillips, Adetola A. Kassim, Lori C. Jordan, Muktar H. Aliyu, Brittany V. Covert, Micha Tags: Research Article Source Type: research
Study Finds Link Between Cancer Diagnosis, Stroke Risk
Title: Study Finds Link Between Cancer Diagnosis, Stroke RiskCategory: Health NewsCreated: 1/7/2015 12:00:00 AMLast Editorial Review: 1/8/2015 12:00:00 AM
Source: MedicineNet Cancer General - January 8, 2015 Category: Cancer & Oncology Source Type: news
Childhood Cancer Survivors Who’ve Had One Stroke at Risk of Second
Rate is double that of people without cancer who've lived through one stroke, study finds
Source: The Doctors Lounge - Oncology - August 26, 2015 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Cardiology, Neurology, Oncology, Pediatrics, News, Source Type: news
Childhood Cancer Survivors Who've Had One Stroke at Risk of Second
Rate is double that of people without cancer who've lived through one stroke, study finds
Source: Cancercompass News: Other Cancer - August 27, 2015 Category: Cancer & Oncology Source Type: news
