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Experiences and actions related to living with type 1 diabetes during the COVID-19 pandemic in Norway: a qualitative study conducted during July to December 2020
Conclusions Patients experienced an increased psychosocial burden of T1DM and difficulties from a disrupted daily life affecting T1DM self-management routines. Uncertainty-reducing behaviours and actions to adapt to the situation provided a general sense of coping despite these difficulties. Tailored information and follow-up by telephone or video call was emphasised to reduce uncertainly distress and support adequate diabetes T1DM self-management.
Source: BMJ Open - April 7, 2022 Category: General Medicine Authors: Pleym, K., Iversen, M. M., Broström, A. Tags: Open access, Diabetes and Endocrinology, COVID-19 Source Type: research

Modelling the potential health and economic benefits of reducing population sitting time in Australia
CONCLUSIONS: Excessive sedentary time results in considerable population health burden in Australia. This paper describes the development of the first Australian sedentary behaviour model that can be used to predict the long term consequences of interventions targeted at reducing sedentary behaviour through reductions in sitting time. These estimates may be used by decision makers when prioritising healthcare resources and investing in preventative public health initiatives.PMID:35305678 | DOI:10.1186/s12966-022-01276-2
Source: Health Physics - March 20, 2022 Category: Physics Authors: Phuong Nguyen Jaithri Ananthapavan Eng Joo Tan Paul Crosland Steve J Bowe Lan Gao David W Dunstan Marj Moodie Source Type: research

The impact of COVID-19 on the comorbidities: A review of recent updates for combating it
Saudi J Biol Sci. 2022 Feb 10. doi: 10.1016/j.sjbs.2022.02.006. Online ahead of print.ABSTRACTCoronavirus disease is caused by the SARS-CoV-2. The virus first appeared in Wuhan (China) in December 2019 and has spread globally. Till now, it affected 26.9 Crore peoples and 53 Lakh deaths in 224 countries and territories. With the emergence of variants like Omicron, the COVID-19 cases grew exponentially, with thousands of deaths. The general symptoms of COVID-19 include fever, sore throat, cough, lung infections, and, in severe cases, acute respiratory distress syndrome, sepsis, and death. SARS-CoV-2 predominantly affects the...
Source: Cancer Control - February 15, 2022 Category: Cancer & Oncology Authors: Jonaid Ahmad Malik Sakeel Ahmed Mrunal Shinde Mohammed Hajjaj Saeid Al-Marmash Saleh Alghamdi Arshad Hussain Sirajudheen Anwar Source Type: research

Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
Ultrason Sonochem. 2021 Oct 21;80:105805. doi: 10.1016/j.ultsonch.2021.105805. Online ahead of print.ABSTRACTRecent advances in ultrasound (US) have shown its great potential in biomedical applications as diagnostic and therapeutic tools. The coupling of ultrasound-assisted drug delivery systems with nanobiomaterials possessing tailor-made functions has been shown to remove the limitations of conventional drug delivery systems. The low-frequency ultrasound has significantly enhanced the targeted drug delivery effect and efficacy, reducing limitations posed by conventional treatments such as a limited therapeutic window. Th...
Source: Ultrasonics Sonochemistry - October 27, 2021 Category: Chemistry Authors: Sze Shin Low Chang Nong Lim Maxine Yew Wai Siong Chai Liang Ee Low Sivakumar Manickam Beng Ti Tey Pau Loke Show Source Type: research

A Potential Role of the CD47/SIRPalpha Axis in COVID-19 Pathogenesis
Curr Issues Mol Biol. 2021 Sep 22;43(3):1212-1225. doi: 10.3390/cimb43030086.ABSTRACTThe coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Most SARS-CoV-2 infections are mild or even asymptomatic. However, a small fraction of infected individuals develops severe, life-threatening disease, which is caused by an uncontrolled immune response resulting in hyperinflammation. However, the factors predisposing individuals to severe disease remain poorly understood. Here, we show that levels of CD47, which is known to mediate immune escape in cancer and virus-infected cells, are elevated in SARS-CoV-2-infected ...
Source: Current Issues in Molecular Biology - October 26, 2021 Category: Molecular Biology Authors: Katie-May McLaughlin Denisa Bojkova Joshua D Kandler Marco Bechtel Philipp Reus Trang Le Florian Rothweiler Julian U G Wagner Andreas Weigert Sandra Ciesek Mark N Wass Martin Michaelis Jindrich Cinatl Source Type: research

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