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Total 88 results found since Jan 2013.

Unlocking Cardiovascular Health
In 2011, the Centers for Disease Control and Prevention published the “Ten Great Public Health Achievements—United States, 2001–2010.”1 Cardiovascular disease (CVD) prevention made the list. Indeed, the combination of reductions in major cardiovascular risk factors, such as elevated blood pressure, high cholesterol, and smoking, combined with improvements in t reatments led to a substantial reduction in the prevalence of stroke and coronary heart disease over the past decades. Unfortunately, heart disease and stroke continue to be responsible for more deaths than cancer and lung diseases combined.
Source: Primary Care: Clinics in Office Practice - August 30, 2023 Category: Primary Care Authors: Anthony J. Viera Tags: Preface Source Type: research

Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage. Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored ...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news

Loneliness Can Cut Survival After a Cancer Diagnosis: Study
MONDAY, June 5, 2023 -- There ’s a " loneliness epidemic " in the United States, and feelings of isolation have been linked to heart disease, stroke and other health conditions. Now, new research suggests that cancer survivors who feel lonely may be...
Source: Drugs.com - Daily MedNews - June 5, 2023 Category: General Medicine Source Type: news

ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol
Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting medical chart,” says Blendermann, a real estate agent in Prior Lake, Minnesota. Yet Blendermann’s routine lab results weren’t alarming. At checkups, her low-density lipoprotein (LDL), or “bad,” cholesterol hovered around the 100 milligrams-per-...
Source: Science of Aging Knowledge Environment - March 16, 2023 Category: Geriatrics Source Type: research

Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Finding better ways to fight heart disease and accelerate cardiac care progress
Cardiovascular disease is the leading cause of death in the United States, claiming more lives than all forms of cancer combined. Heart disease and stroke are among the forms of cardiovascular disease. In 2019,  nearly 900,000 people died of cardiovascular disease in the United States, according to the American Heart Association. In Georgia, about 1 in 3 deaths are caused by cardiovascular disease, according to the Georgia Department of Public Health. Most of these deaths are premature and preventable.…
Source: bizjournals.com Health Care:Physician Practices headlines - February 9, 2023 Category: American Health Source Type: news

The final puff: Can New Zealand quit smoking for good?
Smoking kills. Ayesha Verrall has seen it up close. As a young resident physician in New Zealand’s public hospitals in the 2000s, Verrall watched smokers come into the emergency ward every night, struggling to breathe with their damaged lungs. Later, as an infectious disease specialist, she saw how smoking exacerbated illness in individuals diagnosed with tuberculosis and HIV/AIDS. She would tell them: “The best thing you can do to promote your health, other than take the pills, is to quit smoking.” Verrall is still urging citizens to give up cigarettes—no longer just one by one, but by the thousands. As New...
Source: ScienceNOW - December 9, 2022 Category: Science Source Type: news

Comment on: Insurance-mandated weight management program completion before bariatric surgery provides no long-term clinical benefit
By 2030, 1 in 2 American adults is projected to have obesity and 1 in 4 clinically severe obesity. Obesity represents a serious public health issue because it is a major risk factor for many major, noncommunicable diseases, such as type 2 diabetes, coronary heart disease, stroke, chronic obstructive pulmonary disease, and cancer, and independently predicts overall mortality. The burden of obesity on medical spending is also significant, with $1861 in excess annual medical costs per adult with obesity and $3097 per adult with severe obesity —accounting for $173 billion annually in the United States [1].
Source: Surgery for Obesity and Related Diseases - November 15, 2022 Category: Surgery Authors: Hamlet Gasoyan, David B. Sarwer, Michael B. Rothberg Tags: Editorial comment Source Type: research

Precertification criteria for bariatric surgery should be based on evidence
By 2030, one in two American adults is projected to have obesity and one in four clinically severe obesity. Obesity represents a serious public health issue because it is a major risk factor for many major, non-communicable diseases, such as type 2 diabetes, coronary heart disease, stroke, chronic obstructive pulmonary disease, and cancer, and independently predicts overall mortality. The burden of obesity on medical spending is also significant, with $1,861 excess annual medical costs per adult with obesity and $3,097 per adult with severe obesity – accounting for $173 billion annually in the United States.
Source: Surgery for Obesity and Related Diseases - November 15, 2022 Category: Surgery Authors: Hamlet Gasoyan, David B. Sarwer, Michael B. Rothberg Source Type: research

Preoperative preparation and premedication of bariatric surgical patient
Marina Varbanova, Brittany Maggard, Rainer LenhardtSaudi Journal of Anaesthesia 2022 16(3):287-298 The prevalence of obesity has tripled worldwide over the past four decades. The United States has the highest rates of obesity, with 88% of the population being overweight and 36% obese. The UK has the sixth highest prevalence of obesity. The problem of obesity is not isolated to the developed world and has increasingly become an issue in the developing world as well. Obesity carries an increased risk of many serious diseases and health conditions, including type 2 diabetes, heart disease, stroke, sleep...
Source: Saudi Journal of Anaesthesia - June 20, 2022 Category: Anesthesiology Authors: Marina Varbanova Brittany Maggard Rainer Lenhardt Source Type: research

Ban On Menthol Cigarettes, Cigars Proposed By FDA
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 28, 2022 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston menthol ban Source Type: news

Long-term exposure to ambient fine particulate matter (PM2.5) and associations with cardiopulmonary diseases and lung cancer in Taiwan: a nationwide longitudinal cohort study
ConclusionsLong-term exposure to intermediate levels of ambient PM2.5 was associated with cardiopulmonary health outcomes. Our study adds value to future application and national burden of disease estimation in evaluating the health co-benefits from ambient air pollution reduction policy in Asian countries.
Source: International Journal of Epidemiology - April 26, 2022 Category: Epidemiology Source Type: research

Characteristics of family nurse practitioners and their preparation for practice in rural vs urban employment settings
Approximately 50 million people, 20% of the population of the United States, live in areas designated as rural (U.S.  Census Bureau, 2018). Rural Americans are more likely to die from heart disease, cancer, chronic lower respiratory disease, and stroke compared to their urban counterparts (Rural Health Information (RHI), 2019b). Deaths from unintentional injury are approximately 50% higher in rural areas (Cente rs for Disease Control and Prevention (CDC), 2017). Increasing rates of substance abuse disorders, depression, and suicidality in rural settings continue to outpace rates in urban settings (Gale, Janis, Coburn,& Rochford, 2019).
Source: Nursing Outlook - February 22, 2022 Category: Nursing Authors: Stacy M. Stellflug, Peter Buerhaus, David Auerbach Source Type: research

New ERLEADA ® (apalutamide) Analysis Demonstrates Rapid, Deep Prostate-Specific Antigen (PSA) Response in Patients with Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
SAN FRANCISCO, Feb. 14, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new real-world evidence data showing the initiation of ERLEADA® (apalutamide) results in high rates of rapid and deep prostate-specific antigen (PSA) response among patients with metastatic castration-sensitive prostate cancer (mCSPC). In a separate post-hoc analysis of the registrational Phase 3 SPARTAN and TITAN studies, rapid and deep PSA responses with ERLEADA® were associated with improvement in patient-reported outcomes (PROs) related to quality of life, physical wellbeing, pain, and fatigue intensity. The...
Source: Johnson and Johnson - February 14, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news