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New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study
Conclusions: Pre-injury psychiatric and pre-injury headache/migraine symptoms are risk factors for worse functional and post-concussive outcomes at 3- and 6-months post-mTBI. mTBI patients presenting to acute care should be evaluated for psychiatric and headache/migraine history, with lower thresholds for providing TBI education/resources, surveillance, and follow-up/referrals. Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT01565551. Introduction Traumatic brain injury (TBI) remains a significant cause of morbidity and mortality worldwide. In 2013 ~2.8 million TBI cases were recorded an...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

I ’ ve Been Seeing a Therapist for Years, So Why Am I Not Getting Better?
The answer: We need to address what’s happening inside the office as well as stigma. During the creation of the documentary Going Sane I interviewed Cindy Bulik. She is perhaps the most important researcher on anorexia today. She lives between UNC where she is a distinguished Professor of Eating Disorders and Sweden where she is a professor at the Karolinska Institute. Her current research is exploring genetic influences on anorexia and by the end of our interview she asked if my entire family would be willing to give a sample of blood for the study. She is not the single-minded professor oblivious to social customs tha...
Source: Psych Central - October 10, 2017 Category: Psychiatry Authors: Josh Sabey Tags: Disabilities Disorders Editorials Essays Medications Motivation and Inspiration Policy and Advocacy Psychology Psychotherapy Suicide Treatment Child Development child therapy Clinical Outcome evidence-based practices evidence Source Type: news