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The LITFL Review 095
Welcome to the challenging 95th edition! The LITFL Review is your regular and reliable source for the highest highlights, sneakiest sneak peaks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the best and brightest from the blogosphere, the podcast video/audiosphere and the rest of the Web 2.0 social media jungle to find the most fantastic EM/CC FOAM (Free Open Access Meducation) around. The Most Fair Dinkum Ripper Beaut of the Week emimdoc Top spot this week heads over to David at emimdoc with his post on A Note to Conference Organiz...
Source: Life in the Fast Lane - February 18, 2013 Category: Emergency Medicine Doctors Authors: Kane Guthrie Tags: Education eLearning Emergency Medicine Featured Health Intensive Care LITFL review LITFL R/V Source Type: blogs

Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins." Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Pandemic Fears: What the AIDS Battle Should Teach Us About COVID-19
By ANISH KOKA, MD As the globe faces a novel, highly transmissible, lethal virus, I am most struck by a medicine cabinet that is embarrassingly empty for doctors in this battle.  This means much of the debate centers on mitigation of spread of the virus.  Tempers flare over discussions on travel bans, social distancing, and self quarantines, yet the inescapable fact remains that the medical community can do little more than support the varying fractions of patients who progress from mild to severe and life threatening disease.  This isn’t meant to minimize the massive efforts brought to bear to keep pat...
Source: The Health Care Blog - March 12, 2020 Category: Consumer Health News Authors: Christina Liu Tags: CORVID-19 Health Policy Patients Physicians AIDS Anish Koka AZT coronavirus COVID-19 FDA novel coronavirus Pandemic Source Type: blogs

Two cortisone stories involving Peekaboo and yours truly …
First, the news about Peekaboo. When I met with the vet a few days ago, he repeated that we wouldn’t be able to give her the current anti-inflammatory drug forever. Too bad, since she eagerly takes it in her wet food in the morning, and it seems to have no side effects. Oh well. He suggested I substitute it with a drug called Contramal, which is basically Tramadol, and with another one that contains quercetin (I checked it out, it’s okay, so she’s on that now). Tramadol is a different story. That’s the drug that Piccolo was on for some time last summer, and I am CONVINCED (although I have no proof, ...
Source: Margaret's Corner - September 7, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll cortisone Medrol Source Type: blogs

Review of ICER Report on Treatment Options for Multiple Myeloma
Who is ICER? ICER is the Institute for Clinical and Economic Review.  As far as I can tell, it is funded primarily by insurance companies and by nonprofit organizations who, in turn, are funded by insurance companies.  They claim some funding by the federal government as well.  Other members include pharmaceutical companies who apparently participate in order to have some voice in ICER's proceedings.  A quick Google search shows that the title of many of ICER's documents is "Building Trust through Rationing," which I believe is their mantra and suggests that rationing health care is their real purpose....
Source: Myeloma Hope - June 12, 2016 Category: Cancer & Oncology Tags: ICER myeloma report Source Type: blogs