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Fungal pathogens and COVID-19
Curr Opin Microbiol. 2023 Aug 23;75:102365. doi: 10.1016/j.mib.2023.102365. Online ahead of print.ABSTRACTCOVID-19 pandemic highlighted the complications of secondary fungal infections that occurred globally in severe cases of coronavirus disease managed in the intensive care units. Furthermore, varied underlying host factors, such as preexisting immunosuppression, the use of immunomodulatory agents, and invasive procedures predisposing lung tissues to fungal colonization and proliferation, caused increased susceptibility to fungal infections in COVID-19 patient populations. These invasive fungal infections directly impact...
Source: Current Opinion in Microbiology - August 25, 2023 Category: Microbiology Authors: Ashutosh Singh Amtoj Kaur Anuradha Chowdhary Source Type: research

COVID-19 Associated Mucormycosis
AbstractMucormycosis is a life-threatening opportunistic fungal infection seen in immunocompromised states. Rising incidence of mucormycosis among Coronavirus Disease-2019 infected individuals is an increasing concern in India. The disease which was endemic has blown out to become an epidemic. The purpose of this research is to study the epidemiology, management and outcome of Coronavirus Disease-2019 Associated Mucormycosis (CAM) cases. Additionally, the role of diabetes and steroids in the causation of CAM was determined. A hospital-based observational study was conducted at a tertiary care centre involving cases with rh...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - June 10, 2023 Category: ENT & OMF Source Type: research

Epidemiology of COVID-19 –Associated Mucormycosis
AbstractPurpose of the ReviewTo describe the epidemiology and risk factors for Coronavirus disease-19 (COVID-19) –associated mucormycosis (CAM) based on current published literature.Recent FindingsCOVID-19 is associated with an increased risk of secondary infections. Mucormycosis is an uncommon invasive fungal infection that typically affects people with immunocompromising conditions and uncontrolled diabetes. Treatment of mucormycosis is challenging and is associated with high mortality even with standard care. During the second wave of the COVID 19 pandemic, an abnormally high number of CAM cases were seen particularly...
Source: Current Fungal Infection Reports - May 3, 2023 Category: Infectious Diseases Source Type: research

Clinicopathological association of mucormycosis in COVID 19 pandemic
CONCLUSIONS: The infection with COVID-19 definitely increases the odds of contracting mucormycosis, but most of the cases had diabetes mellitus. So, it is possible that COVID-19 virus predisposes individuals to invasive fungal infection by precipitating DM.PMID:36656219 | DOI:10.4103/ijpm.ijpm_699_21
Source: Indian Journal of Pathology and Microbiology - January 19, 2023 Category: Pathology Authors: Mradul Varshney Ayushi Saxena Nidhi Binnani Vanita Kumar S P Vyas Source Type: research

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