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Specialty: Biomedical Science
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Total 342 results found since Jan 2013.
15-lipoxygenase and cyclooxygenase expression profile and their related modulators in COVID-19 infection
After the outbreak of COVID-19 infection, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection led to disability, hospitalization and death of a large number of people around the world [1]. This virus belongs to the Coronaviridae family that is a single-stranded RNA virus (positive-sense) and causes the spectrum of clinical manifestations in infected patients ranging from fever, cough, chest and body pain, myalgia, dyspnea, headache to mortality [2]. Adult male and elderly are more vulnerable to the disease, and cardiac, diabetic, and metabolic diseases are considered as main risk factors for this infection [3].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - September 3, 2023 Category: Biomedical Science Authors: Sara Kianfar, Vahid Salimi, Alireza Jahangirifard, Seyed Bashir Mirtajani, Mohammad Amin Vaezi, Jila Yavarian, Talat Mokhtari-Azad, Masoumeh Tavakoli-Yaraki Tags: Original research article Source Type: research
A Comparison of the Effects of Dexamethasone and Methylprednisolone, Used on Level-3 Intensive Care COVID-19 Patients, on Mortality: A Multi-Center Retrospective Study
CONCLUSION: Corticosteroids are shown to be beneficial in critical COVID-19, but the role of early corticosteroids in mild COVID-19 patients remains unclear. The anti-inflammatory effects of corticosteroids may have a positive effect by reducing mortality in severe COVID-19 patients. Although dexamethasone was first used for this purpose, methylprednisolone was found to be as effective at standard doses. Methylprednisolone administered at standard doses was associated with greater PaO2/FiO2 ratios than dexamethasone, especially in the severe group requiring MV. High dose pulse steroid doses are closely associated with mort...
Source: Journal of Korean Medical Science - July 25, 2023 Category: Biomedical Science Authors: Ahmet Sari Osman Ekinci Kemal Tolga Sara çoğlu Recep Bal ık Mesut Aslan Yelda Bal ık Ceren Önal Murat Aslan Semra Cevher Aylin Parmaks ız Şeule Vatansever M ünire Canan Çicek Özge Sayın Ayan Gaye Şensöz Çelik A çelya Toprak Mehmet Y ılmaz Source Type: research
Risk Factors Associated with COVID-19 Mortality in the State of Durango, Mexico
Int J Med Sci. 2023 May 27;20(8):993-999. doi: 10.7150/ijms.82591. eCollection 2023.ABSTRACTThe coronavirus disease 2019 (COVID-19) has caused over six million deaths worldwide since its emergence in Wuhan China, factors associated with COVID-19 mortality, such as comorbidities, age, and observed symptomatology still remain a major subject of study. In the present work, a total of 16,345 SARS-CoV-2 positive cases from Durango Mexico diagnosed from May 2020 to December 2021 were analyzed to establish an association of COVID-19 mortality with clinical and demographic variables in a case-control study. Selected variables incl...
Source: International Journal of Medical Sciences - July 24, 2023 Category: Biomedical Science Authors: Sebasti án Eduardo González Villarreal Sergio Manuel Salas Pacheco Fernando V ázquez Alaniz Mar ía Irene Betancourt Conde Jos é Manuel Salas Pacheco Karla Cecilia Castillo Vazquez Alma Cristina Salas Leal Omar Alejandro Tremillo Maldonado Juan Antoni Source Type: research
