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15-lipoxygenase and cyclooxygenase expression profile and their related modulators in COVID-19 infection
After the outbreak of COVID-19 infection, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection led to disability, hospitalization and death of a large number of people around the world [1]. This virus belongs to the Coronaviridae family that is a single-stranded RNA virus (positive-sense) and causes the spectrum of clinical manifestations in infected patients ranging from fever, cough, chest and body pain, myalgia, dyspnea, headache to mortality [2]. Adult male and elderly are more vulnerable to the disease, and cardiac, diabetic, and metabolic diseases are considered as main risk factors for this infection [3].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - September 3, 2023 Category: Biomedical Science Authors: Sara Kianfar, Vahid Salimi, Alireza Jahangirifard, Seyed Bashir Mirtajani, Mohammad Amin Vaezi, Jila Yavarian, Talat Mokhtari-Azad, Masoumeh Tavakoli-Yaraki Tags: Original research article Source Type: research

Vaccine effectiveness in symptom and viral load mitigation in COVID-19 breakthrough infections in South Korea
by Jieun Jang, Hyopin Jeong, Bong-Hwa Kim, Sura An, Hye-Ryun Yang, Sunjoo Kim ObjectivesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine effectiveness in coronavirus disease (COVID-19) patients with breakthrough infections has not been established in South Korea. To address this, we assessed the impact of vaccination on symptom occurrence and viral load. MethodsWe performed a retrospective cohort study of 9,030 COVID-19 patients enrolled between February and November 2021. The impact of vaccination on the incidence of symptoms and viral load as indicated by cycle threshold (Ct) values ofRdRp andE genes ...
Source: PLoS One - August 16, 2023 Category: Biomedical Science Authors: Jieun Jang Source Type: research

Gut Microbiota Dysbiosis Correlates With Long COVID-19 at One-Year After Discharge
CONCLUSION: This study demonstrated the presence of long COVID-19 which correlates with gut microbiota dysbiosis in RPs at one-year after discharge, indicating gut microbiota may play an important role in long COVID-19.PMID:37069814 | PMC:PMC10111044 | DOI:10.3346/jkms.2023.38.e120
Source: Journal of Korean Medical Science - April 18, 2023 Category: Biomedical Science Authors: Dongmei Zhang Yaya Zhou Yanling Ma Ping Chen Jian Tang Bohan Yang Hui Li Mengyuan Liang YuE Xue Yao Liu Jianchu Zhang Xiaorong Wang Source Type: research

3- to 24-month Follow-up on COVID-19 with Pulmonary Tuberculosis Survivors after Discharge: Results from a Prospective, Multicenter Study
CONCLUSION: The proportion of long symptoms in COVID-19 with PTB survivors decreased over time, while nearly one in six still experience persistent symptoms with a higher proportion of anxiety. The recurrence of PTB and the psychological support of COVID-19 with PTB after discharge require more attention.PMID:36597288 | DOI:10.3967/bes2022.126
Source: Biomedical and Environmental Sciences : BES - January 4, 2023 Category: Biomedical Science Authors: Jing Ya Wang Xing Yu Zong Gui Hui Wu Yuan Lin Qi Hui Zhen Li Xin Yu Ji Lin Tong Lei Zhang Ming Bo Yang Pu Ye Yang Ji Ke Li Fu Rong Xiao Lin Song Zhang Yun Hong Hu Hong De Liu Shou Fang Xu Sheng Sun Wei Wu Ya Mao Min Qing Li Hao Hua Hou Zhao Yuan Gong Yang Source Type: research

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