Morphological and behavioral analysis of Slc35f1-deficient mice revealed no neurodevelopmental phenotype
Brain Struct Funct. 2023 Mar 23. doi: 10.1007/s00429-023-02629-8. Online ahead of print.ABSTRACTSLC35F1 is a member of the sugar-like carrier (SLC) superfamily that is expressed in the mammalian brain. Malfunction of SLC35F1 in humans is associated with neurodevelopmental disorders. To get insight into the possible roles of Slc35f1 in the brain, we generated Slc35f1-deficient mice. The Slc35f1-deficient mice are viable and survive into adulthood, which allowed examining adult Slc35f1-deficient mice on the anatomical as well as behavioral level. In humans, mutation in the SLC35F1 gene can induce a Rett syndrome-like phenoty...
Source: Brain Structure and Function - March 23, 2023 Category: Neuroscience Authors: Julia Sophie Ehlers Katharina Bracke Viola von Bohlen Und Halbach Florian Siegerist Nicole Endlich Oliver von Bohlen Und Halbach Source Type: research

Morphological and behavioral analysis of Slc35f1-deficient mice revealed no neurodevelopmental phenotype
Brain Struct Funct. 2023 Mar 23. doi: 10.1007/s00429-023-02629-8. Online ahead of print.ABSTRACTSLC35F1 is a member of the sugar-like carrier (SLC) superfamily that is expressed in the mammalian brain. Malfunction of SLC35F1 in humans is associated with neurodevelopmental disorders. To get insight into the possible roles of Slc35f1 in the brain, we generated Slc35f1-deficient mice. The Slc35f1-deficient mice are viable and survive into adulthood, which allowed examining adult Slc35f1-deficient mice on the anatomical as well as behavioral level. In humans, mutation in the SLC35F1 gene can induce a Rett syndrome-like phenoty...
Source: Brain Structure and Function - March 23, 2023 Category: Neuroscience Authors: Julia Sophie Ehlers Katharina Bracke Viola von Bohlen Und Halbach Florian Siegerist Nicole Endlich Oliver von Bohlen Und Halbach Source Type: research

Morphological and behavioral analysis of Slc35f1-deficient mice revealed no neurodevelopmental phenotype
Brain Struct Funct. 2023 Mar 23. doi: 10.1007/s00429-023-02629-8. Online ahead of print.ABSTRACTSLC35F1 is a member of the sugar-like carrier (SLC) superfamily that is expressed in the mammalian brain. Malfunction of SLC35F1 in humans is associated with neurodevelopmental disorders. To get insight into the possible roles of Slc35f1 in the brain, we generated Slc35f1-deficient mice. The Slc35f1-deficient mice are viable and survive into adulthood, which allowed examining adult Slc35f1-deficient mice on the anatomical as well as behavioral level. In humans, mutation in the SLC35F1 gene can induce a Rett syndrome-like phenoty...
Source: Brain Structure and Function - March 23, 2023 Category: Neuroscience Authors: Julia Sophie Ehlers Katharina Bracke Viola von Bohlen Und Halbach Florian Siegerist Nicole Endlich Oliver von Bohlen Und Halbach Source Type: research

Morphological and behavioral analysis of Slc35f1-deficient mice revealed no neurodevelopmental phenotype
Brain Struct Funct. 2023 Mar 23. doi: 10.1007/s00429-023-02629-8. Online ahead of print.ABSTRACTSLC35F1 is a member of the sugar-like carrier (SLC) superfamily that is expressed in the mammalian brain. Malfunction of SLC35F1 in humans is associated with neurodevelopmental disorders. To get insight into the possible roles of Slc35f1 in the brain, we generated Slc35f1-deficient mice. The Slc35f1-deficient mice are viable and survive into adulthood, which allowed examining adult Slc35f1-deficient mice on the anatomical as well as behavioral level. In humans, mutation in the SLC35F1 gene can induce a Rett syndrome-like phenoty...
Source: Brain Structure and Function - March 23, 2023 Category: Neuroscience Authors: Julia Sophie Ehlers Katharina Bracke Viola von Bohlen Und Halbach Florian Siegerist Nicole Endlich Oliver von Bohlen Und Halbach Source Type: research

Morphological and behavioral analysis of Slc35f1-deficient mice revealed no neurodevelopmental phenotype
Brain Struct Funct. 2023 Mar 23. doi: 10.1007/s00429-023-02629-8. Online ahead of print.ABSTRACTSLC35F1 is a member of the sugar-like carrier (SLC) superfamily that is expressed in the mammalian brain. Malfunction of SLC35F1 in humans is associated with neurodevelopmental disorders. To get insight into the possible roles of Slc35f1 in the brain, we generated Slc35f1-deficient mice. The Slc35f1-deficient mice are viable and survive into adulthood, which allowed examining adult Slc35f1-deficient mice on the anatomical as well as behavioral level. In humans, mutation in the SLC35F1 gene can induce a Rett syndrome-like phenoty...
Source: Brain Structure and Function - March 23, 2023 Category: Neuroscience Authors: Julia Sophie Ehlers Katharina Bracke Viola von Bohlen Und Halbach Florian Siegerist Nicole Endlich Oliver von Bohlen Und Halbach Source Type: research