Epilepsy Research Now in 3D: Harnessing the Power of Brain Organoids in Epilepsy
Epilepsy Curr. 2022 Jan 6;22(2):135-136. doi: 10.1177/15357597211070391. eCollection 2022 Mar-Apr.ABSTRACTBrain organoids represent a powerful tool for studying human neurological diseases, particularly those that affect brain growth and structure. However, many diseases manifest with clear evidence of physiological and network abnormality in the absence of anatomical changes, raising the question of whether organoids possess sufficient neural network complexity to model these conditions. Here, we explore the network-level functions of brain organoids using calcium sensor imaging and extracellular recording approaches that...
Source: Epilepsy Currents - April 21, 2022 Category: Neurology Authors: Christina Gross Source Type: research