VATS Decortication Versus IR Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema
Condition:   Empyema, Pleural Interventions:   Other: Video assisted thorascopic decortication;   Other: Interventional radiology guided chest tube insertion with MIST2 trial fibrinolytics Sponsor:   Queen's University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 12, 2018 Category: Research Source Type: clinical trials

Treatment of voluminous and complicated superficial slow-flow vascular malformations with sirolimus (PERFORMUS): protocol for a multicenter phase 2 trial with a randomized observational-phase design
The objective of this trial is to evaluate the efficacy and safety of sirolimus in children with complicated superficial slow-flow VMs.Methods/designThis French multicenter randomized observational-phase, phase 2 trial aims to include 50 pediatric patients 6 to 18  years old who have slow-flow (lymphatic, venous or lymphatico-venous) voluminous complicated superficial VM. Patients will be followed up for 12 months. All patients will start with an observational period (no treatment). Then at a time randomly selected between month 4 and month 8, they will swi tch to the experimental period (switch time), when they ...
Source: Trials - June 27, 2018 Category: Research Source Type: clinical trials

Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNA
Conditions:   Lung Cancer;   Lung Cancer, Nonsmall Cell;   Lung Cancer, Small Cell Intervention:   Sponsors:   HKGepitherapeutics;   Kazakh Research Institute of Oncology/Radiology;   Montreal EpiTerapia Inc.;   Canada-Kazakhstan EpiTerapia Inc.;   Kazakhstan-Canada Research Center of Genetics and Epitherapy Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2018 Category: Research Source Type: clinical trials

Detection of Prostate Cancer With Non-invasive Method Based on DNA Methylation of Circulated Tumor DNA, PBMC
Conditions:   Prostate Cancer;   Prostate Adenocarcinoma;   Prostate Cancer Metastatic Intervention:   Sponsors:   HKGepitherapeutics;   Kazakh Research Institute of Oncology/Radiology;   Montreal EpiTerapia Inc.;   Canada-Kazakhstan EpiTerapia Inc.;   Kazakhstan-Canada Research Center of Genetics and Epitherapy Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 11, 2018 Category: Research Source Type: clinical trials

Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer
Condition:   Head and Neck Cancer Interventions:   Procedure: MRI;   Procedure: Blood Draw;   Behavioral: Questionnaires Sponsors:   M.D. Anderson Cancer Center;   Radiological Society of North America;   The Royal Australian and New Zealand College of Radiologists Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2018 Category: Research Source Type: clinical trials