RELEASE (REdressing Long-tErm Antidepressant uSE): protocol for a 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1 in general practice
This study aims to det ermine the effectiveness of two multi-strategy interventions (RELEASE and RELEASE+) in supporting the safe cessation of long-term antidepressants, estimate cost-effectiveness, and evaluate implementation strategies.MethodsDesign3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1. Setting: primary care general practices in southeast Queensland, Australia. Population: adults 18 years or older taking antidepressants for longer than 1 year. Practices will be randomised on a 1.5:1:1 ratio of Usual care:RELEASE:RELEASE+. Intervention: RELEASE for patients inclu...
Source: Trials - September 28, 2023 Category: Research Source Type: clinical trials
A Pain and Coordination Plan for Reduced Opioid Use After Accidental Injuries
Conditions: Opioid Use; Injury Traumatic; Pain, Postoperative Interventions: Other: PAC-plan Sponsors: University of Oslo; Oslo University Hospital; The Norwegian Research Fund for General Practice Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2023 Category: Research Source Type: clinical trials
Combined Exercise and Nutrition Intervention for Possible Sarcopenia Among Older Adults in Primary Care
Condition: Sarcopenia Intervention: Behavioral: Experimental group Sponsor: Kyunghee University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials
Combined Exercise and Nutrition Intervention for Possible Sarcopenia Among Older Adults in Primary Care
Conditions: Sarcopenia Interventions: Behavioral: Experimental group Sponsors: Kyunghee University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials
Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India
Conditions: Schizophrenia; Schizophrenia and Related Disorders; Psychosocial Functioning Interventions: Behavioral: Community care for People with Schizophrenia in India (COPSI); Behavioral: mindLAMP Mobile Application Sponsors: Harvard Medical School (HMS and HSDM); Beth Israel Deaconess Medical Center; Sangath; National Institute of Mental Health and Neuro Sciences, India; All India Institute of Medical Sciences, Bhopal Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials
