Two Experts Help Sort Out The New Generation Of Anticoagulants
Don’t miss this very practical discussion about the new generation of anticoagulants over on CardioExchange. Here are a few excerpts. Christian Thomas Ruff: I believe the addition of the 3 currently approved novel anticoagulants (dabigatran, rivaroxaban, and apixaban) will eventually translate into a greater proportion of eligible patients being treated; it certainly has in my practice… Although I think it is important to continue to develop reversal agents for the novel anticoagulants, I don’t think the lack of such an agent is sufficient reason to avoid using a novel anticoagulant. I think that price is on...
Source: CardioBrief - January 17, 2013 Category: Cardiology Authors: Larry Husten Tags: Uncategorized Anticoagulant apixaban atrial fibrillation dabigatran Eliquis Pradaxa rivaroxaban stroke warfarin Xarelto Source Type: blogs

FDA approval of apixaban for stroke prevention in AF: The "tipping point" for novel oral anticoagulants
With three novel drugs—dabigatran, rivaroxaban, and now apixaban—approved for stroke prevention in AF, the tide is changing on oral anticoagulation. (Source: Blogs@theHeart.org)
Source: Blogs@theHeart.org - January 11, 2013 Category: Cardiology Authors: theheart.org Tags: Clotblog with Dr Samuel Goldhaber Source Type: blogs

Top medicine articles for December 2012-January 2013
Here are my suggestions for some of the top articles in medicine for December 2012-January 2013: Among former Olympic athletes, engagement in disciplines with high intensity exercise did not bring a survival benefit http://buff.ly/UmY9Ur Non-benzodiazepine hypnotics (Z drugs - eszopiclone, zaleplon, zolpidem) are effective for treatment of adult insomnia http://buff.ly/UZC1g9 Bringing surgical history to life | BMJ http://buff.ly/UZCeQC -- Things change fast in surgery. Within a single generation, ways of operating that had been stable for decades have been overturned. New drugs have revolutionized what were o...
Source: Clinical Cases and Images - Blog - January 11, 2013 Category: Professors and Educators Tags: Health News of the Day Source Type: blogs

Substitutes For Coumadin In Atrial Fibrillation
<p>As of the last week of December, with the FDA approval of apixaban (Eliquis), there are now three new anticoagulant drugs available to use as substitutes for Coumadin (warfarin) in people with atrial fibrillation not associated with valvular heart disease.&#160; The other two Coumadin substitutes are dabigatran (Pradaxa) and rivaroxaban (Xarelto).&#160; All three of these drugs have attractive advantages over Coumadin - but there are also potential drawbacks to all three.</p>...<p><a href="http://clk.about.com/?zi=1/1hc&#038;zu=http://heartdisease.about.com/b/2013/01/11/substitutes-...
Source: About.com Heart Disease - January 7, 2013 Category: Cardiology Source Type: blogs

Right Bundle Branch Block with New Anterior ST elevation
An elderly female with no known history of CAD presented to the ED as a walk-in with vomiting and upper abdominal discomfort.  The following ECG was recorded at t = 0:There is sinus rhythm with Right Bundle Branch Block and ST elevation in leads V1 and V2, suspicious for STEMI. The computerized QRS duration is 138 ms.   A previous ECG was found:There is an RSR' with right ventricular conduction delay and downsloping ST depression in V1 that is reminiscent of Brugada pattern.  The computerized QRS duration is 84 ms.  The ST elevation is confirmed to be new.The cath lab was activated but the interven...
Source: Dr. Smith's ECG Blog - January 4, 2013 Category: Cardiology Authors: Steve Smith Source Type: blogs

Wardround 2xii11
Our Topic for discussion this week was Driving and Medical illness with regard to the DVLA medical regulations. It was instructive to look how these would impact on patients on the ward.One way to bring driving history into our routine assessments is to regard driving as part of our ambulation/motility questions. If it is missed during initial clerking it should then come up as we approach discharge planning.The DVLA has its at a glance guide which can be easily assessed but a good aide memoire for fitness to drive at patient.co.uk.I missed the discussion about avoiding finding yourself out of your dept...
Source: MJM Wardrounds - December 2, 2011 Category: Universities & Medical Training Source Type: blogs