RELEASE (REdressing Long-tErm Antidepressant uSE): protocol for a 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1 in general practice
This study aims to det ermine the effectiveness of two multi-strategy interventions (RELEASE and RELEASE+) in supporting the safe cessation of long-term antidepressants, estimate cost-effectiveness, and evaluate implementation strategies.MethodsDesign3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1. Setting: primary care general practices in southeast Queensland, Australia. Population: adults 18  years or older taking antidepressants for longer than 1 year. Practices will be randomised on a 1.5:1:1 ratio of Usual care:RELEASE:RELEASE+. Intervention: RELEASE for patients inclu...
Source: Trials - September 28, 2023 Category: Research Source Type: clinical trials

Optimizing blood pressure control by an Information Communication Technology-supported case management (PIA study): study protocol for a cluster-randomized controlled trial of a delegation model for general practices
DiscussionIt is hypothesized that the PIA-Intervention will improve the quality of BP care. Perspectively, it may constitute an important health service model for primary care in Germany.Trial registrationGerman Clinical Trials Register DRKS00012680. Registered on May 10, 2019 (Source: Trials)
Source: Trials - October 25, 2021 Category: Research Source Type: clinical trials

Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury
Conditions:   Traumatic Brain Injury;   Trauma, Nervous System;   Reperfusion Injury;   Ischemia, Brain Interventions:   Device: CellAegis Technologies autoRIC device;   Other: Best Practice Management of Traumatic Brain Injury Sponsors:   St. Michael's Hospital, Toronto;   Dr. Markus Ziesmann;   Dr. Shawn Rhind;   Dr. Sandro Rizoli;   Canadian Institute for Military and Veteran Health Research Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 15, 2017 Category: Research Source Type: clinical trials