The medical basis of vampires and other medical myths [PODCAST]
“Where did the myth of vampires come from? Like many myths, it is based partly in fact. A blood disorder called porphyria, which has has been with us for millennia, became prevalent among the nobility and royalty of Eastern Europe. A genetic disorder, it becomes more common with inbreeding. Porphyria is a malfunction in the […]Find jobs at  Careers by  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 8, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Oncology/Hematology Source Type: blogs

A health librarian at the theatre: The Madness of George III
It ' s been several weeks since I " went " to the theatre, but I have just watched the Nottingham Playhouse ' s production of this Alan Bennett play, on theNational Theatre Live YouTube channel.I saw the film (called The Madness of King George) some years back and I was aware of the idea that the King was not mad, but had porphyria.  The clue was the blue urine, which none of the doctors (in the play) thought was important.But I had not realised that view has been questioned.  There are several articles in the medical literature, many by Timothy Peters of the University of Birmingham (UK).  It...
Source: Browsing - June 13, 2020 Category: Databases & Libraries Tags: medical history psychiatry Source Type: blogs

Adverse effects of hydroxychloroquine
In case you were ever stupid enough to follow Trump’s lead you would have already injected ultraviolets in your eyeballs by now to save you from Covid and maybe bathed in Domestos or sulfuric acid or both! Anyway, his latest bullshine claim is that he’s been taking the antimalarial drug hydroxychloroquine to keep Covid at bay. Well, for starters there is no evidence that this drug acts as a prophylactic against infection with SARS CoV-2 or indeed any pathogen other than the causative agent of otherwise drug-resistant malaria. It’s primary use is in treating lupus. There was some testing done weeks ago to...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 19, 2020 Category: Science Authors: David Bradley Tags: Health and Medicine Source Type: blogs

Funtabulously Frivolous Friday Five 278 – GoT Version
It's Friday. Boggle your brain with FFFF challenge and some old fashioned trivia. Funtabulously Frivolous Friday Five 278 - Game of Thrones Style The post Funtabulously Frivolous Friday Five 278 – GoT Version appeared first on Life in the Fast Lane • LITFL • Medical Blog. (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - April 12, 2019 Category: Emergency Medicine Authors: Dr Neil Long Tags: FFFF aortic dissection bipolar crapper Fibrodysplasia ossificans progressiva Game of thrones GoT Grey scale John Harrington John Snow Johra Jon Snow King George II King George III Kit Harrington porphyria Targaryen Toilet Source Type: blogs

Opioids: The pendulum has swung too far in the wrong direction
I’m a 43-year-old physician who retired due to illness at the age of 39. I have a rare genetic disease called acute intermittent porphyria (AIP). It’s an extremely painful and disabling illness. Due to an enzyme deficiency in the heme biosynthesis pathway in the liver, porphyrin precursors accumulate and are neurotoxic causing visceral neuropathy. The symptoms of the disease are neurological with the most notable being abdominal pain. It is a neuropathic pain which has a burning sensation that is unbearable. The pain is similar to what I’d imagine it would feel like to have a blowtorch against my stomach and my back....
Source: Kevin, M.D. - Medical Weblog - March 31, 2018 Category: General Medicine Authors: < a href="" rel="tag" > Lisa Kehrberg, MD < /a > Tags: Physician Pain Management Primary Care Source Type: blogs

The Porphyria Research Consortium: A Partnership Between the American Porphyria Foundation and Physician Researchers
Editor’s Note: For more on patient advocacy groups, like the Porphyria Research Consortium, check out our AM Last Page, entitled “Realizing the Potential of Patient Organizations in Translational Research—Delivering Treatments for Rare Diseases.” By: Desiree Lyon Howe, executive director, American Porphyria Foundation The American Porphyria Foundation (APF) has been instrumental in facilitating porphyria research for over thirty years. The porphyrias are a group of disorders caused by enzyme deficiencies in the heme biosynthetic pathway that affect the Central Nervous System and/or the skin. The coll...
Source: Academic Medicine Blog - September 18, 2014 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Guest Perspective American Porphyria Foundation basic science research biomedical research patient advocacy patient organization Source Type: blogs

Acute Intermittent Porphyria
Acute intermittent porphyria is a disease marked by an enzyme deficiency Pathophysiology of acute intermittent porphyria The post Acute Intermittent Porphyria appeared first on InsideSurgery Medical Information Blog. (Source: Inside Surgery)
Source: Inside Surgery - July 20, 2013 Category: Surgeons Authors: Editor Tags: Hematology Source Type: blogs

The acute porphyrias
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - April 8, 2013 Category: Internists and Doctors of Medicine Tags: gastroenterology miscellaneous endocrinology Source Type: blogs

Rasmussen’s encephalitis-MRI
7 Year old male child with history of chronic epilepsy of few months duration with history of hospitalization for Brain inflammation previously. MRI shows right hemispheric volume loss  with atrophy with areas of encephalomalacia-gliosis with ipsilateral ventriculomegaly with normal ICA & MCA flow voids and normal calvarium, sinuses, sphenoid wing & orbital roof possibly representing Rasmussen’s encephalitis. Teaching points by Dr MGK Murthy,  Mr Umamaheswar, Dr sreenivas metta, Mr Hameed  This is chronic inflammation of the Brain with infiltration of T Lymphocytes affecting...
Source: Sumer's Radiology Site - March 13, 2013 Category: Radiologists Authors: Sumer Sethi Source Type: blogs

USMLE Questions – Characteristic Disease Findings
The United States Medical Licensing Examination (USMLE) is designed to emphasize knowledge of clinical scenarios and clinical pearls, even on Step I. Listed below are some commonly encountered disease findings and characteristics. Feature Disease 45, X chromosome Turner’s syndrome 5-HIAA increased in urine Carcinoid syndrome Aganglionic rectum Hirschsrpung’s disease Apple-core sign on barium enema Colon cancer Arched back (opisthotonos) Tetanus Argyll-Robertson pupil Syphilis Ash leaf on forehead Tuberous sclerosis Auer rods  Acute myelogenous leukemia Austin Flint murmur Aortic regurgitation...
Source: Inside Surgery - January 18, 2013 Category: Surgeons Authors: Editor Tags: Surgpedia USMLE diseases findings VMA water hammer pulse Source Type: blogs