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Population Pharmacokinetics of Antiepileptic in Pediatrics
Condition:   Epilepsy Interventions:   Biological: Valproic acid;   Biological: carbamazepine;   Biological: phenobarbital;   Biological: phenytoin;   Biological: levetiracetam;   Biological: lamotrigine;   Biological: topiramate;   Biological: oxcarbazepine;   Biological: stiripentol;   Biological: clobazam Sponsor:   Assistance Publique - Hôpitaux de Paris Recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 20, 2017 Category: Research Source Type: clinical trials

Emergency treatment with levetiracetam or phenytoin in status epilepticus in children —the EcLiPSE study: study protocol for a randomised controlled trial
DiscussionThis clinical trial will determine whether phenytoin or levetiracetam is more effective as an intravenous second-line agent for CSE, and provide evidence for management recommendations. In addition, this trial will also provide data on which of these therapies is safer in this setting.Trial registrationISRCTN identifier,ISRCTN22567894. Registered on 27 August 2015EudraCT identifier,2014-002188-13. Registered on 21 May 2014NIHR HTA Grant:12/127/134 (Source: Trials)
Source: Trials - June 19, 2017 Category: Research Source Type: clinical trials