PIPAC and FOLFOX for Gastric Cancer Peritoneal Cancer
Conditions: Gastric Cancer; Peritoneal Carcinomatosis Intervention: Drug: Combined Doxorubicin and Cisplatin Pressurized IntraPeritoneal Aerosol Chemotherapy With Systemic FOLFOX chemotherapy Sponsors: Vilnius University; Vilnius University Hospital Santaros Klinikos; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 9, 2022 Category: Research Source Type: clinical trials
Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery for gastric carcinoma at high risk of peritoneal carcinomatosis: short and long-term outcomes (GOETH STUDY) —a collaborative randomized controlled trial by ACOI, FONDAZIONE AIOM, SIC, SICE, and SICO
This study compares the efficacy of prophylactic surgery (radical gastric resection, appendectomy, resection of the round ligament of the liver, and bilateral adnexectomy) plus hybrid CO2 HIPEC system versus standard surgery in patients with T3-T4 N0-N + gastric adenocarcinoma. Patients will be randomly assigned (1:1 ratio) to the experimental arm or standard surgery. The primary endpoint is to establish the difference in disease-free survival between the groups. The secondary objective is to compare the safety and tolerability of prophylacti c surgery plus HIPEC CO2 versus standard surgery.DiscussionConsidering the p...
Source: Trials - December 1, 2022 Category: Research Source Type: clinical trials
A Predictive Model to Predict the Individualized Risk of Major Postoperative Complications After a Surgery of Resection With Hyperthermic Peritoneal Chemotherapy HIPEC for Peritoneal Carcinomatosis Based on Pre and Peroperative Criteria: Which Patients Require Intensive Monitoring?
Condition: Peritoneal Carcinomatosis Intervention: Procedure: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy Sponsor: CHU de Reims Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2022 Category: Research Source Type: clinical trials
