Expert position paper on use of proton pump inhibitors in patients with cardiovascular disease and antithrombotic therapy
Source: Eur Heart J Area: News The European Society of Cardiology NSTEMI and STEMI guidelines and an ACCF/ACG/AHA consensus document recommend treatment with proton pump inhibitors (PPIs) in patients treated with dual antiplatelet treatment (DAPT) during the initial phase of an acute coronary syndrome (ACS), particularly in patients with a history of GI bleeding or peptic ulcer. Several studies have raised concerns that many PPIs, especially omeprazole, might diminish the antiplatelet effects of clopidogrel, most likely through inhibition of CYP2C19 and, consequently, the conversion of clopidogrel into its active metaboli...
Source: NeLM - Cardiovascular Medicine - February 21, 2013 Category: Cardiology Source Type: news

Some Reassurance About Proton Pump Inhibitors and Risk of Osteoporotic Fractures
Despite limitations, this study lends some reassurance that risk of osteoporosis is not likely to overshadow the benefit of proton pump inhibitors in preventing recurrent peptic ulcer, esophageal reflux symptoms, and esophageal cancer risk. (Source: Consultant Live)
Source: Consultant Live - February 11, 2013 Category: Primary Care Source Type: news

'Bad' Gut Bacteria May Help Control Diabetes
A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to immunologists at the Virginia Bioinformatics Institute of Virginia Tech. Usually the villain in studies of gastric cancer and peptic ulcers, Helicobacter pylori infect about half of the world's population although most infected individuals don't get sick. The bacterium's dwindling numbers coincide with the epidemic of obesity and diabetes in developed countries. "H... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 10, 2013 Category: Consumer Health News Tags: Diabetes Source Type: news

The Evolving Challenges of Helicobacter pylori Disease, Diagnostics, and Treatment, Part II
Abstract: Helicobacter pylori infects half of the world's population; is associated with several severe gastric illnesses, including peptic ulcer disease and gastric cancer; and causes significant morbidity in its host. Several trends in the field of H. pylori have evolved recently, drastically changing the way that these infections are managed. Part I of this article was published in the February 1, 2013 issue of Clinical Microbiology Newsletter (Vol. 35, No. 3) and provided a concise overview of the pathogenesis and epidemiology of the disease, as well as a review of recommendations for the use of laboratory tests f...
Source: Clinical Microbiology Newsletter - February 6, 2013 Category: Microbiology Authors: Marc Roger Couturier Source Type: news

What You Need to Know About Heartburn Related Digestive Disorders
Talking to your doctor is important whenever you have a concern about your health. If that concern is connected to your digestive system, particularly that which is related to the symptom of heartburn, then this information on heartburn related digestive disorders can give  you some ideas of what questions to ask your doctor, and may answer some of your questions now. Related Information: What is GERD? What is a hiatal hernia? What are peptic ulcers? What are gallstones? What You Need to Know About Heartburn Related Digestive Disorders originally appeared on About.com Heartburn / GERD on Wednesday, February 6t...
Source: About Heartburn / Acid Reflux - February 6, 2013 Category: Consumer Health News Source Type: news

What Are Your Stomach Pain Symptoms Trying to Tell You?
If you are suffering from stomach pain, you need to find the cause before you can start a treatment. Here are a few of the conditions that can cause stomach pain. Heartburn Related Resources: Meal Planning Tips for Preventing Heartburn Dining Out Without Heartburn Foods with Little Risk of Causing Heartburn Preventing Nighttime Heartburn Peptic Ulcer Related Resources Surgery for Peptic Ulcers Complications of Peptic Ulcers Peptic Ulcer Warning Signs Peptic Ulcers in Children Gallstone Related Resources: What is the Gallbladder? What are Gallstones? What Increases the Risk of Developing...
Source: About Heartburn / Acid Reflux - February 6, 2013 Category: Consumer Health News Source Type: news

Causes of Heartburn
You've just enjoyed a big meal and are relaxing in front of the TV when it happens. A burning sensation begins to build in the upper abdomen, behind the breastbone, and makes your chest feel like it's on fire. The burning and pain may travel from your diaphragm all the way to your throat, and may be accompanied with a sour taste and the sensation of food re-entering your mouth. You're suffering from severe heartburn. Despite the name, heartburn has nothing to do with the heart. It's a digestive problem that occurs when stomach acid comes into contact with the lining of the esophagus, causing irritation. Most people suffe...
Source: About Heartburn / Acid Reflux - February 6, 2013 Category: Consumer Health News Source Type: news

Gene variant boosts ulcer susceptibility in NSAID users
A single nucleotide polymorphism in the cytochrome P450 2C gene cluster influences the risk for peptic ulcer disease in people taking non-steroidal anti-inflammatory drugs, a study reveals. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 31, 2013 Category: Gastroenterology Source Type: news

How to Get Heartburn Relief
If you experience heartburn because of having gastroesophageal reflux disease (GERD), a hiatal hernia, a peptic ulcer, or some other digestive disorder, finding heartburn relief is important. Before starting any treatment or remedy for heartburn, you should talk to your doctor about what is best for you to consider. Learn how you can get heartburn relief. Related Resources: Nighttime Heartburn Heartburn During Pregnancy What You Need to Know About Heartburn Treatment and Remedies Do You Always Need Medication to Control Heartburn? Tips for Calming Nighttime Heartburn How to Get Heartburn Relief originally ...
Source: About Heartburn / Acid Reflux - January 22, 2013 Category: Consumer Health News Source Type: news

The Evolving Challenges of Helicobacter pylori Disease, Diagnostics, and Treatment, Part I
Abstract: Helicobacter pylori infects half of the world's population; is associated with several severe gastric illnesses, including peptic ulcer disease and gastric cancer; and causes significant morbidity in its host. Several trends in the field of H. pylori have evolved recently, drastically changing the way that these infections are managed. Part I of this article reviews the current challenges facing H. pylori disease management and provides both clinicians and laboratorians with a concise overview of its pathogenesis, epidemiology, and testing strategies. Part II of this article will be published in the next iss...
Source: Clinical Microbiology Newsletter - January 22, 2013 Category: Microbiology Authors: Marc Roger Couturier Source Type: news

10 Things to Stop Doing If You Have Heartburn
<p>If you suffer from chronic heartburn, you know how it can affect your life. In your efforts to get your heartburn under control, you have probably thought about all the things you should be doing. That's great! But also important is remembering what NOT to do.  So here's a list of <a href="http://heartburn.about.com/od/dailylife/tp/10-Things-To-Stop-Doing-If-Have-Heartburn.htm" target="_blank">10 things you should stop doing if you have heartburn</a>.</p> <p><strong>Related Information:</strong></p> <ul> <li><a href="http://clk.a...
Source: About Heartburn / Acid Reflux - January 16, 2013 Category: Consumer Health News Source Type: news

Cardiology: Images in Clinical Medicine
Editor: V. Dimov, M.D., Cleveland ClinicMobile Large Left Atrial Thrombus.NEJM, 12/2014Wellens ' syndrome, associated with severe stenosis of the left anterior descending artery.NEJM, 12/2014Endocardial Calcification in Beh çet ' s Disease.NEJM, 11/2013.An Electrocardiographic Sine Wave in Hyperkalemia. NEJM, 05/2012.Left Main Coronary Artery Thrombosis. NEJM, 04/2012.Homozygous familial hypercholesterolaemia. Lancet, 04/2012.Endocardial fibroelastosis of the heart. Lancet, 02/2012.Internal-Carotid-Artery Dissection and Cranial-Nerve Palsies. NEJM, 12/2011.Thrombosis of a Mechanical Mitral Valve. NEJM, 12/2011.Pneumoperic...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Cardiology Images Source Type: news

Gastroenterology: Images in Clinical Medicine
Editor: V. Dimov, M.D., Assistant Professor at University of ChicagoGrey Turner ' s sign suggesting retroperitoneal haemorrhage. Lancet, 05/2014.Abdominal-Wall Varices in the Budd –Chiari Syndrome. NEJM, 05/2014.Biliary ileus. Lancet, 07/2012.Meconium-like Ileus in Cystic Fibrosis. NEJM, 05/2012.Achalasia. NEJM, 04/2012.Intestinal Infestation with Ancylostoma ceylanicum. NEJM, 03/2012.Kayser-Fleischer Rings in Wilson ' s Disease. NEJM, 03/2012.Barium Aspiration. NEJM, 03/2012.Pneumopericardium Associated with a Peptic Ulcer. NEJM, 12/2011.Abdominal calcifications secondary to cysticercosis. Lancet, 12/2011.Retinopat...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Gastroenterology Images Source Type: news