Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
Conditions:   Perforated Peptic Ulcer;   Fast Track Surgery;   Perforated Bowel;   Post-Op Complication;   Emergencies Intervention:   Other: ERAS protocol Sponsor:   All India Institute of Medical Sciences, Bhubaneswar Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 10, 2022 Category: Research Source Type: clinical trials

Stop of proton-pump inhibitor treatment in patients with liver cirrhosis (STOPPIT): study protocol for a prospective, multicentre, controlled, randomized, double-blind trial
DiscussionThe STOPPIT trial is the first clinical trial to study the effects of PPI withdrawal on relevant outcome variables in patients with complicated liver cirrhosis. If the hypothesis that PPI withdrawal improves clinical outcomes of cirrhosis patients is confirmed, this would argue for a strong restriction of the currently liberal prescription practice of PPIs in this population. If, on the other hand, the trial demonstrates an increased risk of gastrointestinal bleeding events in patients after PPI withdrawal, this could create a rationale for a more liberal, prophylactic PPI treatment in patients with liver cirrhos...
Source: Trials - April 12, 2022 Category: Research Source Type: clinical trials

Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding
Condition:   Peptic Ulcer Hemorrhage Intervention:   Drug: Tranexamic Acid Powder Sponsor:   National Cheng-Kung University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2022 Category: Research Source Type: clinical trials