INOVIO Announces Positive Preliminary Results from Second Cohort of Phase 1/2 Trial with INO-3107 for the Treatment of Recurrent Respiratory Papillomatosis
10 of 11 patients (91%) had a reduction in number of surgical interventions, measured from Day 0 to one year following initial treatment; 4 of the 10 patients did not need any surgery Treatment with INO-3107 achieved statistical significance... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 16, 2023 Category: Pharmaceuticals Source Type: clinical trials

INOVIO Reports Positive Interim Phase 1/2 Results for INO-3107 for the Treatment of Recurrent Respiratory Papillomatosis
Treatment with INO-3107 resulted in 16 of 21 (76%) participants with a reduction in number of surgical interventions compared with previous year; 6 participants required no surgical intervention during the trial INO-3107 demonstrated statistical... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 13, 2022 Category: Pharmaceuticals Source Type: clinical trials

A Phase I Study of Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis
Conditions:   Recurrent Respiratory Papillomatosis;   Papillomavirus Infections;   Papillomaviridae Intervention:   Drug: PRGN-2012 Sponsor:   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2021 Category: Research Source Type: clinical trials

Lenvatinib and Pembrolizumab In HPV-associated RRP
Conditions:   Human Papilloma Virus;   Recurrent Respiratory Papillomatosis Interventions:   Drug: Lenvatinib;   Drug: Pembrolizumab Sponsors:   Massachusetts General Hospital;   Eisai Inc.;   Merck Sharp & Dohme Corp. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2020 Category: Research Source Type: clinical trials