Optimization of the antibiotic management of diabetic foot infections: protocol for two randomized controlled trials
DiscussionBoth parallel RCTs will respond to frequent questions regarding the duration of antibiotic use in the both major subsets of DFIs, to ensure the quality of care, and to avoid unnecessary excesses in terms of surgery and antibiotic use.Trial registrationClinicalTrials.gov,NCT04081792. Registered on 4 September 2019. (Source: Trials)
Source: Trials - January 7, 2020 Category: Research Source Type: clinical trials
Short or Long Antibiotic Regimes in Orthopaedics (SOLARIO): a randomised controlled open-label non-inferiority trial of duration of systemic antibiotics in adults with orthopaedic infection treated operatively with local antibiotic therapy
This study aims to assess a treatment strategy that may enable the reduction of systemic antibiotic use for patients with orthopaedic infection. If this strategy is non-inferior, this will be to the advantage of patients and contribute to antimicrobial stewardship.Trial registrationClinicaltrials.gov,NCT03806166. Registered on 11 November 2019. (Source: Trials)
Source: Trials - December 8, 2019 Category: Research Source Type: clinical trials
Ceftriaxone as Home IV for Staph Infections
Conditions: Staphylococcal Infections; Osteomyelitis; CNS Infection; Septic Arthritis; Diabetic Foot Infection; Vertebral Osteomyelitis; Abscess; Coagulase Negative Staphylococcal Infection Interventions: Drug: Ceftriaxone; Drug: Usual Antibiotics (Cloxacillin, Cefazolin, Daptomycin) Sponsor: Vancouver Island Health Authority Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 28, 2019 Category: Research Source Type: clinical trials
