EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial
This study aims to assess the effect of MRA administration in the early phase of kidney transplantation (KT) among recipients of ECD grafts on mid-term graft function.Methods/designThis is a multicenter, double-blind, placebo-controlled, randomized clinical trial. Patients on hemodialysis and undergoing a single or a dual KT from an ECD will be eligible for inclusion. We plan to randomize 132 patients. Included patients will be randomized (1:1) to receive either eplerenone 25 mg every 12 h during 4 days (the first dose being administered just prior to KT) or placebo. The primary outcome is graft function at 3 months, ...
Source: Trials - October 30, 2018 Category: Research Source Type: clinical trials
Pediatric Risk of Hypothyroidism With Iodinated Contrast Media
Condition: Hypothyroidism Interventions: Drug: Iohexol; Drug: Iodixanol; Drug: Iopromide Sponsors: GE Healthcare; Bayer; Duke Clinical Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 15, 2018 Category: Research Source Type: clinical trials
