Obstetric Cholestasis Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)
DiscussionCurrent practice in the UK at the time of trial commencement for the treatment of ICP is inconsistent, with some units routinely prescribing UDCA, others prescribing very little and the remainder offering it variably. Our previous pilot trial of UDCA in women with ICP demonstrated that the trial would be feasible, and the research question remains active and unanswered. Results are highly likely to influence clinical practice, through direct management and impact on national and international guidelines.Trial registrationISRCTN registry, ID:ISRCTN91918806. Prospectively registered on 27 August 2015. (Source: Trials)
Source: Trials - November 27, 2018 Category: Research Source Type: clinical trials

Long Term Safety & Efficacy Study Evaluating The Effect of A4250 in Children With PFIC Types 1 & 2
Conditions: Progressive Familial Intrahepatic Cholestasis Type 1 (PFIC1); Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC2) Intervention: Drug: A4250 Sponsor: Albireo Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 6, 2018 Category: Research Source Type: clinical trials

Efficacy and Safety of Maralixibat (SHP625) in the Treatment of Participants With Progressive Familial Intrahepatic Cholestasis (PFIC)
Condition: Cholestasis Interventions: Drug: Maralixibat; Drug: Placebo Sponsor: Shire Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2017 Category: Research Source Type: clinical trials