Cholesterol increases risk of Alzheimer's and heart disease
(University of Colorado Denver) Using insights gained from studying two much rarer disorders, Down Syndrome and Niemann Pick-C disease, researchers at the Linda Crnic Institute for Down Syndrome and the Department of Neurology of the University of Colorado School of Medicine found that cholesterol wreaks havoc on the orderly process of cell division, leading to defective daughter cells throughout the body. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 15, 2013 Category: Global & Universal Source Type: news
NIH clinical trial begins for treatment of rare, fatal neurological disorder
A clinical trial to evaluate a drug candidate called cyclodextrin as a possible treatment for Niemann-Pick disease type C1 (NPC), a rare and fatal genetic disease, will start today, researchers announced. Scientists from the NIH"s National Center for Advancing Translational Sciences (NCATS) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) will conduct the clinical trial at the NIH Clinical Center. Reaching this trial stage required collaboration among government, industry, patient advocacy groups and academic researchers. NHGRI is one of the collaborating institutions on the r...
Source: NHGRI-Related News - January 23, 2013 Category: Genetics & Stem Cells Source Type: news
NIH clinical trial begins for treatment of rare, fatal neurological disorder
(NIH/National Center for Advancing Translational Sciences (NCATS)) A clinical trial to evaluate a drug candidate called cyclodextrin as a possible treatment for Niemann-Pick disease type C1 (NPC), a rare and fatal genetic disease, will start today, researchers announced. Scientists from the NIH's National Center for Advancing Translational Sciences (NCATS) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) will conduct the clinical trial at the NIH Clinical Center. Reaching this trial stage required collaboration among government, industry, patient advocacy groups and academic r...
Source: EurekAlert! - Medicine and Health - January 23, 2013 Category: Global & Universal Source Type: news
Researchers Identify Protein Essential in Transmission of Ebola Virus
Researchers identified a novel small molecule that inhibits EboV entry into cells by more than 99 percent; they found that the target of the inhibitor is the cell protein Niemann-Pick C1 (Source: BWH News)
Source: BWH News - August 24, 2011 Category: Hospital Management Source Type: news
