National Health Service (NHS) Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Oral versus intravenous antibiotic treatment for bone and joint infections (OVIVA): study protocol for a randomised controlled trial
Discussion If our results demonstrate non-inferiority of orally administered antibiotic therapy, this trial is likely to facilitate a dramatically improved patient experience and alleviate a substantial financial burden on healthcare services. Trial registration ISRCTN91566927 - 14/02/2013 (Source: Trials)
Source: Trials - December 21, 2015 Category: Research Source Type: clinical trials

Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) for diagnosis and management of bladder outlet obstruction in men: study protocol for a randomised controlled trial
Discussion The general population has an increased life-expectancy and, as men get older, their prostates enlarge and potentially cause benign prostatic obstruction (BPO) which often requires surgery. Furthermore, voiding symptoms become increasingly prevalent, some of which may not be due to BPO. Therefore, as the population ages, more operations will be considered to relieve BPO, some of which may not actually be appropriate. Hence, there is sustained interest in the diagnostic pathway and this trial could improve the chances of an accurate diagnosis and reduce overall numbers of surgical interventi...
Source: Trials - December 10, 2015 Category: Research Source Type: clinical trials

Self-Harm Intervention: Family Therapy (SHIFT), a study protocol for a randomised controlled trial of family therapy versus treatment as usual for young people seen after a second or subsequent episode of self-harm
Discussion SHIFT will provide a well-powered evaluation of the clinical and cost effectiveness of Family Therapy for young people who have self-harmed on more than one occasion. The study will be reported in 2016, and the results will inform clinical practice thereafter. Trial registration ISRCTN59793150. 26 January 2009. (Source: Trials)
Source: Trials - November 4, 2015 Category: Research Source Type: clinical trials

Alternative forms of hydration in patients with cancer in the last days of life: study protocol for a randomised controlled trial
Discussion A randomised controlled trial of clinically assisted hydration in end-of-life care is urgently required. This feasibility study will allow methodological and ethical issues to be understood and addressed to ensure that a robust, adequately powered, randomised controlled trial is designed. Trial registration ClinicalTrials.gov NCT02344927 (registered 4 June 2014). (Source: Trials)
Source: Trials - October 14, 2015 Category: Research Source Type: clinical trials

Prevention of delirium (POD) for older people in hospital: study protocol for a randomised controlled feasibility trial
Discussion This feasibility study will be used to gather data to inform the design of a future definitive randomised controlled trial. Trial registration ISRCTN01187372. Registered 13 March 2014. (Source: Trials)
Source: Trials - August 8, 2015 Category: Research Source Type: clinical trials

The Health Of Patients’ Eyes (HOPE) Glaucoma study. The effectiveness of a ‘glaucoma personal record’ for newly diagnosed glaucoma patients: study protocol for a randomised controlled trial
This study aims to determine whether providing newly diagnosed glaucoma patients with a personalised client-held eye health summary (‘glaucoma personal record’), improves patients’ knowledge of their glaucoma condition. A potential long-term benefit could be improved self-management and henceforth a slower rate of deterioration. Methods/Design HOPE Glaucoma is a 3-year, prospective, parallel-group, pragmatic, single-centred, randomised controlled trial. An anticipated 122 adults, newly diagnosed with glaucoma (including ocular hyper...
Source: Trials - August 7, 2015 Category: Research Source Type: clinical trials

A Comparative RCT of Brief Internet-based Compassionate Mind Training and Cognitive-behavioral Therapy for Mothers and Their Babies
Condition: Comparison of Internet-based CBT and CMTInterventions: Behavioral: Cognitive Behavioral Therapy; Behavioral: Compassionate Mind TrainingSponsors: i4Health; National Health Service, United Kingdom (in process); Compassionate Mind FoundationRecruiting - verified June 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 5, 2015 Category: Research Source Type: clinical trials