Mixed Results for Oral Lupus Drug in Phase II
(MedPage Today) -- What could be the first oral medication specific for systemic lupus erythematosus (SLE) was more effective than placebo in a randomized phase II trial, though the results were something less than a home run. With 288 patients... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 16, 2022 Category: Rheumatology Source Type: news

Ankylosing Spondylitis: Another Step Toward Individualized Therapy
(MedPage Today) -- Whether patients with ankylosing spondylitis (AS) would improve substantially with tumor necrosis factor (TNF) inhibitor therapy was predicted with moderate to high accuracy based only on a standard lab test and two measures... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 15, 2022 Category: Rheumatology Source Type: news

Does Knee Replacement 'Prehab' Help?
(MedPage Today) -- A pre-surgery exercise program for people scheduled for total knee replacement provided neither improved joint function in the days after the procedure nor better ability to perform ordinary activities in the first 6 months... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 10, 2022 Category: Rheumatology Source Type: news

Gauging Cardiovascular Risk in Psoriatic Disease: It's Complicated
(MedPage Today) -- Clinicians treating patients with psoriasis or psoriatic arthritis should know that certain biomarkers of cardiovascular risk may provide extra information beyond what's included in conventional prediction tools, researchers... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 9, 2022 Category: Rheumatology Source Type: news

Fibromyalgia Patients See Rapid Benefit From Low-Cal Diet
(MedPage Today) -- For nearly three-quarters of obese patients with fibromyalgia, drastic caloric restriction in a small trial led to 30% or greater reduction in symptom severity in only 3 weeks, researchers reported. The findings support an emerging... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 2, 2022 Category: Rheumatology Source Type: news

Kids With IBD Need Close Monitoring as They Grow Up
(MedPage Today) -- The well-known cancer risk accompanying inflammatory bowel disease (IBD) applies even when symptoms begin in childhood or adolescence, a meta-analysis affirmed. Cancer rates in adulthood were approximately doubled compared with... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 2, 2022 Category: Rheumatology Source Type: news

Suspend Methotrexate for RA Patients Getting COVID Vax?
(MedPage Today) -- A COVID-19 vaccine's immunogenicity was increased in rheumatoid arthritis patients when they stopped methotrexate temporarily after each dose in a randomized trial, but this benefit came with a cost. Nearly 80% of patients for... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 23, 2022 Category: Rheumatology Source Type: news

Resistant Hypertension Double in SLE Patients (CME/CE)
(MedPage Today) -- RHTN now seen as a risk factor for SLE patients, and associated with gender, older age, race, and high creatinine levels (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 25, 2019 Category: Rheumatology Source Type: news

Antenatal Steroids Tied to Lower Infant Birth Weight
(MedPage Today) -- Antenatal corticosteroids therapy is " not a one-size-fits-all approach, " researcher says (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 26, 2019 Category: Rheumatology Source Type: news

VTE Risk High in Spine Disease
(MedPage Today) -- More deep venous thrombosis than pulmonary embolism seen in ankylosing spondylitis (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - February 14, 2019 Category: Rheumatology Source Type: news

Biosimilar to Infliximab Switch Yields Similar IBD Outcomes (CME/CE)
(MedPage Today) -- No significant changes in clinical remission, and no new safety signals (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 16, 2019 Category: Rheumatology Source Type: news

Combo RA Tx May Boost Risk for Serious Adverse Events (CME/CE)
(MedPage Today) -- Clinicians should consider risk-benefit ratio of combination biologics, according to meta-analysis (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 3, 2019 Category: Rheumatology Source Type: news

IL-1 and Gout: Proof of Concept vs Cost
(MedPage Today) -- Some experts remain optimistic about targeting IL-1 for gout, but others cite costs (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 30, 2018 Category: Rheumatology Source Type: news

IL-1 Blockade Appears Effective Against Gout
(MedPage Today) -- Canakinumab lowered the risk of attacks by more than half in post-MI patients (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 29, 2018 Category: Rheumatology Source Type: news

Lutikizumab Ineffective for Erosive Hand Osteoarthritis (CME/CE)
(MedPage Today) -- Targeting IL-1 alpha and beta did not improve pain, function, or structural changes (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 28, 2018 Category: Rheumatology Source Type: news