Antiviral Offers 'Glimmer of Hope' in Chronic Hepatitis D
(MedPage Today) -- VIENNA -- Among patients with chronic hepatitis D virus (HDV), subcutaneous treatment with the investigational antiviral bulevirtide led to a combined response of an undetectable HDV RNA level and normalization of alanine aminotransferase... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 23, 2023 Category: Gastroenterology Source Type: news

'Game Changer' in NASH: Resmetirom Hits Endpoints in Pivotal Study
(MedPage Today) -- VIENNA -- The investigational agent resmetirom resolved liver biopsy findings in nonalcoholic steatohepatitis (NASH) more often than placebo, according to the phase III MAESTRO-NASH trial. While 10% of placebo patients achieved... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 23, 2023 Category: Gastroenterology Source Type: news

Transfascial Mesh Fixation During Complex Hernia Repairs: To Skip or Not to Skip?
(MedPage Today) -- Not fixating the mesh in open retromuscular ventral hernia repair (RVHR) was noninferior to fixation, a single-center clinical trial found. Hernia recurrence rates at 1 year were similar between the transfascial suture fixation... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 22, 2023 Category: Gastroenterology Source Type: news

Trial Suggests Optimal Approach to Unresectable CRC Liver Mets
(MedPage Today) -- For patients with initially unresectable colorectal cancer liver metastases, FOLFOXIRI plus bevacizumab (Avastin) was the "preferred" systemic induction regimen for those with a right-sided or RAS- or BRAF V600E-mutated primary... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 21, 2023 Category: Gastroenterology Source Type: news

Pope Discharged; Neurologist Drowns After Saving Daughter; Booze Tied to 61 Diseases
(MedPage Today) -- Note that some links may require subscriptions. Also note that Morning Break will be taking a break on Monday in observance of the Juneteenth's holiday. Look for its return on Tuesday, June 20. Pope Francis has been discharged... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 16, 2023 Category: Gastroenterology Source Type: news

Parents' Goals for Pediatric Palliative Care Change Over Time
(MedPage Today) -- Parents of children in palliative care placed the highest value on the child's quality of life (QoL), but with considerable individual-level variation and substantial change over time, researchers found. In a cohort study of... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 12, 2023 Category: Gastroenterology Source Type: news

Omitting RT Safe in Many Locally Advanced Rectal Cancers
(MedPage Today) -- CHICAGO -- Standard pelvic chemoradiotherapy prior to surgery can be safely omitted in select patients with locally advanced rectal cancer whose tumors respond to neoadjuvant chemotherapy, findings from a large cooperative... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 5, 2023 Category: Gastroenterology Source Type: news

A Close Look at the Data Backing Upadacitinib's Approval in Crohn's
(MedPage Today) -- The selective Janus kinase (JAK) inhibitor upadacitinib (Rinvoq) improved clinical remission and endoscopic response rates compared with placebo in patients with moderate-to-severe Crohn's disease, according to two induction... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 25, 2023 Category: Gastroenterology Source Type: news

Anti-EGFR Rechallenge Boosts PFS in Third-Line Metastatic Colorectal Cancer
(MedPage Today) -- Rechallenge with an EGFR inhibitor in addition to standard therapy led to significantly better progression-free survival (PFS) in third-line metastatic colorectal cancer (mCRC) versus standard therapy alone, a small randomized... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 23, 2023 Category: Gastroenterology Source Type: news

Probiotic Use in NICUs Shows Some Benefits in Newborns With Very Low Birth Weight
(MedPage Today) -- Routine use of probiotics among newborns with very low birth weight in U.S. neonatal intensive care units (NICUs) was associated with a lower risk of necrotizing enterocolitis, but not sepsis or mortality, according to a cohort... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 13, 2023 Category: Gastroenterology Source Type: news

mRNA Vaccine Promising for Pancreatic Cancer
(MedPage Today) -- A personalized mRNA vaccine, used in combination with an immune checkpoint inhibitor and chemotherapy after surgery, induced an immune response in half of treated patients with pancreatic ductal adenocarcinoma (PDAC), a small... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 11, 2023 Category: Gastroenterology Source Type: news

Prophylactic Antibiotics of Little Benefit in Severe Alcoholic Hepatitis
(MedPage Today) -- A 30-day course of prophylactic antibiotics added to standard treatment did not improve survival in patients hospitalized for severe alcohol-related hepatitis, researchers reported. In a clinical trial of 292 patients, 2-month... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 10, 2023 Category: Gastroenterology Source Type: news

Palliative Care No Boon for Patients Undergoing Abdominal Surgery for Cancer
(MedPage Today) -- Specialist palliative care did not improve quality of life for patients undergoing major abdominal surgeries for cancer compared with usual care, the randomized SCOPE trial showed. Adjusted median scores on the Functional Assessment... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 10, 2023 Category: Gastroenterology Source Type: news

Win for Vedolizumab in Recurrent Crohn's Disease
(MedPage Today) -- CHICAGO -- Patients receiving vedolizumab (Entyvio) after undergoing bowel resection for advanced Crohn's disease in a randomized trial were significantly less likely to show endoscopic signs of recurrence compared with placebo... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 8, 2023 Category: Gastroenterology Source Type: news

Even at Stage IV, Immunotherapy Helps in Pancreatic Cancer
(MedPage Today) -- CHICAGO -- Real-world data demonstrate that immunotherapies, broadly defined, prolong survival in stage IV pancreatic cancer compared with standard care, a researcher said here. Records from the U.S. National Cancer Database... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 8, 2023 Category: Gastroenterology Source Type: news