Linaclotide Doubled Bowel Movements in Children With Functional Constipation
(MedPage Today) -- A newly approved option for pediatric patients with functional constipation significantly increased the frequency of bowel movements and improved other burdensome symptoms as well, according to a pivotal phase III trial. Among... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 12, 2024 Category: Gastroenterology Source Type: news

Vaccine 'Promising' for Delaying Relapse in KRAS-Mutated Pancreatic Cancer, CRC
(MedPage Today) -- An investigational therapeutic vaccine appeared to be effective in delaying relapse of KRAS-mutated pancreatic and colorectal cancer (CRC), according to results from the phase I AMPLIFY-201 study. Among 25 patients with pancreatic... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 9, 2024 Category: Gastroenterology Source Type: news

Clinical Challenges: Integrating Diet Into Crohn's Disease Management
(MedPage Today) -- Incorporating diet into Crohn's disease (CD) treatment regimens has some support, with a shift toward a whole-foods nutrition approach for symptom relief and healing. Although far from definitively established, inflammation... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 27, 2023 Category: Gastroenterology Source Type: news

Rectal Botox Injections Improved Fecal Incontinence, Urgency
(MedPage Today) -- Botulinum toxin type A (Botox) injections in the rectum reduced episodes of fecal incontinence and urgency, a randomized controlled trial showed. Among nearly 200 patients in a modified intention-to-treat analysis, the mean... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 22, 2023 Category: Gastroenterology Source Type: news

Ozanimod Did Not Appear to Lead to More Adverse Pregnancy Outcomes
(MedPage Today) -- ORLANDO -- Women with inflammatory bowel disease or relapsing multiple sclerosis who became pregnant while taking the sphingosine-1-phosphate (S1P) receptor modulator ozanimod (Zeposia) did not appear to have a higher risk... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 19, 2023 Category: Gastroenterology Source Type: news

Novel Oral Agent May Dial Down Ulcerative Colitis Severity
(MedPage Today) -- ORLANDO -- For patients diagnosed with moderate to severe ulcerative colitis, the investigational agent icanbelimod had mixed results in reducing the severity of disease within 12 weeks when used as induction and maintenance... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 19, 2023 Category: Gastroenterology Source Type: news

Shingles Vaccine Reduced Zoster Attacks in Patients With IBD
(MedPage Today) -- ORLANDO -- While patients with inflammatory bowel disease (IBD) are historically more prone to herpes zoster attacks, those who received recombinant zoster vaccines had a far lower risk of the painful rash emerging, researchers... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 18, 2023 Category: Gastroenterology Source Type: news

Goodbye, Appendix. Hello, Crohn's Disease?
(MedPage Today) -- ORLANDO – People who undergo appendectomy may have an increased risk for the development of Crohn's disease (CD), but not ulcerative colitis (UC), according to a systematic review and meta-analysis. The meta-analysis showed... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 17, 2023 Category: Gastroenterology Source Type: news

Red Meat Consumption Tied to Higher Chance of UC Flare
(MedPage Today) -- ORLANDO – For people with inflammatory bowel disease (IBD), that hamburger may come with more than just a side of fries -- red meat consumption was linked with a higher risk for ulcerative colitis (UC) flare, researchers... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 17, 2023 Category: Gastroenterology Source Type: news

National Database Study Finds Higher Risk for Barrett ’s Esophagus in IBD
(MedPage Today) -- ORLANDO – People with inflammatory bowel disease (IBD) faced higher odds of Barrett's esophagus (BE) and BE without dysplasia, but not BE-linked malignancy, according to a cross-sectional study. Among patients diagnosed... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 17, 2023 Category: Gastroenterology Source Type: news

Lenvatinib-Pembrolizumab Combo Misses Goal in First-Line HCC Trial
(MedPage Today) -- Combining lenvatinib (Lenvima) with an immune checkpoint inhibitor in the first-line setting for unresectable hepatocellular carcinoma (HCC) failed to significantly improve survival outcomes in an international phase III trial... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 14, 2023 Category: Gastroenterology Source Type: news

EUS-Guided Gastroenterostomy Better Option for Cancer-Related Duodenal Blockages
(MedPage Today) -- Using endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) led to better outcomes in the palliation of malignant gastric outlet obstruction compared with conventional stenting of the duodenum, an international randomized... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 8, 2023 Category: Gastroenterology Source Type: news

Stephen Colbert Has Surgery for Ruptured Appendix
(MedPage Today) -- "Late Show" host Stephen Colbert cancelled this week's episodes while he recovers from an appendectomy, he announced on Threads. "Going forward, all emails to my appendix will be handled by my pancreas," the comedian wrote in... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 28, 2023 Category: Gastroenterology Source Type: news

Biologic Therapy for IBD Not Tied to Higher Risk of Major Heart Events
(MedPage Today) -- In contrast to recent data on tofacitinib (Xeljanz) in rheumatoid arthritis, patients with inflammatory bowel disease (IBD) who received biologic therapies appeared to have a lower risk for a major adverse cardiovascular event... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 28, 2023 Category: Gastroenterology Source Type: news