Does Rheumatoid Arthritis Get Its Start in the Gut?
(MedPage Today) -- Evidence that at least some forms of rheumatoid arthritis (RA) are connected to the intestinal microbiome continues to mount, with a new study showing that antibodies to a common intestinal bacterium appear elevated throughout... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 20, 2022 Category: Gastroenterology Source Type: news

Do Crohn's Patients Do Better With Early Surgery?
(MedPage Today) -- Patients with Crohn's disease who underwent earlier, rather than later, abdominal surgery had fewer cumulative reoperations in the years ahead, though they also had a higher hospitalization risk, a retrospective Danish study... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 20, 2022 Category: Gastroenterology Source Type: news

Probiotics in the ICU Linked to Higher Risk of Central Line Infections, Death
(MedPage Today) -- NASHVILLE, Tenn. -- Among patients with central venous catheters in the intensive care unit (ICU), use of probiotic medications was associated with an increased incidence of central line infections and death, a retrospective... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 19, 2022 Category: Gastroenterology Source Type: news

Extra Pounds May Blunt Benefit of Aspirin in Advanced Colorectal Cancer
(MedPage Today) -- The association between aspirin use following an advanced colorectal cancer diagnosis and better survival was only significant among patients with a normal body mass index (BMI) prediagnosis, a cross-sectional study found. In... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 15, 2022 Category: Gastroenterology Source Type: news

An Intestinal Transplant First; 4-Year Stelara Data in UC; Lymphoma After Anti-TNF
(MedPage Today) -- A 1-year-old girl from Spain is the world's first successful recipient of a multi-visceral intestinal transplant from a controlled donor in asystole. (Reuters) Although probiotics containing the strain Bifidobacterium longum... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 13, 2022 Category: Gastroenterology Source Type: news

Vonoprazan Just as Good or Better Than Lansoprazole for Erosive Esophagitis
(MedPage Today) -- Vonoprazan (Voquezna) was noninferior to lansoprazole (Prevacid) for healing patients with erosive esophagitis, and was superior for maintaining healing, a randomized trial showed. In a modified intention-to-treat analysis including... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 12, 2022 Category: Gastroenterology Source Type: news

One Sigmoidoscopy Yields Long-Term Reduction in CRC Incidence, Death
(MedPage Today) -- Sigmoidoscopy screening reduces the long-term incidence of colorectal cancer (CRC) and mortality, according to pooled data from four randomized trials. In the analysis of nearly 275,000 participants, the cumulative incidence... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 11, 2022 Category: Gastroenterology Source Type: news

POEM Trial Results Hold Firm for Long-Term Efficacy in Achalasia
(MedPage Today) -- Peroral endoscopic myotomy (POEM) may be the best bet as first-line treatment for treatment-naive patients with achalasia, according to long-term trial data. POEM offered greater long-term efficacy and a low risk of treatment... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 6, 2022 Category: Gastroenterology Source Type: news

Can Norovirus Trigger Crohn's? Phase III NASH Trial Flops; Social Isolation in IBD
(MedPage Today) -- Is norovirus infection triggering Crohn's disease in people with certain genetic mutations? (NBC News) The phase III REVERSE trial of obeticholic acid (Ocaliva) for compensated cirrhosis caused by non-alcoholic steatohepatitis... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 6, 2022 Category: Gastroenterology Source Type: news

TETA4 Noninferior to Penicillamine for Stable Wilson's Disease
(MedPage Today) -- Oral maintenance therapy with trientine tetrahydrochloride (TETA4; Cuvrior) was noninferior to penicillamine for patients with stable Wilson's disease, the phase III randomized CHELATE trial showed. In an intention-to-treat... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 3, 2022 Category: Gastroenterology Source Type: news

Higher Risk for Treatment Failure With Vedolizumab in Older IBD Patients
(MedPage Today) -- Treatment with vedolizumab (Entyvio) was associated with a higher risk of treatment failure compared with tumor necrosis factor (TNF) inhibitors in older adults with inflammatory bowel disease (IBD), especially those with Crohn... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 1, 2022 Category: Gastroenterology Source Type: news

FDA Clears AI Polyp Detection Device; IBD and Sexual Issues; Stelara in Pregnancy
(MedPage Today) -- The FDA cleared the artificial intelligence-assisted Skout polyp detection device for adults undergoing colorectal cancer screening and surveillance, Iterative Scopes announced. Nexpowder, an endoscopic hemostasis system that... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 29, 2022 Category: Gastroenterology Source Type: news

FMT Tops Standard of Care for First or Second C. Diff Infections
(MedPage Today) -- Early use of fecal microbiota transplantation (FMT) following a course of antibiotics offered a superior treatment option for patients experiencing a first or second Clostridioides difficile infection, according to a randomized... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 29, 2022 Category: Gastroenterology Source Type: news

Anticipate More Adenomas After FIT-Positive Colonoscopies
(MedPage Today) -- Endoscopists' adenoma detection rate (ADR) during colonoscopies that follow a positive fecal immunochemical test (FIT) was inversely related to the risk for developing interval colorectal cancer (CRC), Dutch researchers found... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 27, 2022 Category: Gastroenterology Source Type: news

Have We Been Overcautious With TNF Inhibitors in Pregnancy?
(MedPage Today) -- What may seem like a prudent approach to treatment of inflammatory bowel disease (IBD) in pregnant women actually represents an overabundance of caution, suggested researchers who found no increased risk from tumor necrosis factor... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 26, 2022 Category: Gastroenterology Source Type: news