A randomised controlled unblinded multicentre non-inferiority trial with activated vitamin D and prednisolone treatment in patients with minimal change nephropathy (ADAPTinMCN)
This study tests the hypothesis that a new treatment regimen in MCN combining reduced dose prednisolone and active vitamin D is as efficient in inducing remission and has fewer and less severe adverse events than standar d prednisolone. Furthermore, we aim to establish models allowing for more personalized medicine based on assessment of the individual’s prednisolone metabolism.MethodsA randomised controlled multicentre non-inferior unblinded trial including 96 adult, incident patients with biopsy-proven MCN, albuminuria> 3 g/day, and an estimated glomerular filtration rate (eGFR)> 30 ml/min from renal de...
Source: Trials - July 12, 2021 Category: Research Source Type: clinical trials
Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome
Conditions: Nephrotic Syndrome; Thromboembolic Disease Interventions: Drug: Dalteparin; Drug: Apixaban Sponsor: University of Aarhus Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 20, 2021 Category: Research Source Type: clinical trials
