Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors
Conditions: Skin-Picking; Trichotillomania (Hair-Pulling Disorder) Interventions: Drug: Memantine; Behavioral: ComB Behavioral Therapy Sponsor: University of Chicago Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2023 Category: Research Source Type: clinical trials
Statistical analysis plan for the motor neuron disease systematic multi-arm adaptive randomised trial (MND-SMART)
DiscussionIn developing the statistical analysis plan, we had to carefully consider several issues such as multiple testing, estimand specification, interim analyses, and statistical analysis of the repeated measurements of ALS-FRS-R. This analysis plan attempts to balance multiple factors, including minimisation of bias, maximising power and precision, and deriving clinically interpretable summaries of treatment effects.Trial registrationEudraCT Number, 2019 –000099-41. Registered 2 October 2019,https://www.clinicaltrialsregister.eu/ctr-search/search?query=mnd-smartClinicalTrials.gov,NCT04302870. Registered 10 March 2020. (Source: Trials)
Source: Trials - January 16, 2023 Category: Research Source Type: clinical trials
Glutamate Inhibitors in Glioblastoma
Condition: Glioblastoma Interventions: Drug: Gabapentin; Drug: Sulfasalazine; Drug: Memantine; Drug: Temozolomide; Radiation: Radiotherapy Sponsors: University of Zurich; Swiss National Science Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 23, 2022 Category: Research Source Type: clinical trials
