OCD tx after SJS on sertraline?
Does anyone know of papers/guidance on SSRI or TCA use for patient with history of stevens johnson syndrome after starting sertraline?
I could only find a couple of case reports in languages I am not fluent in regarding antidepressant rechallenge.
Tried memantine monotherapy with limited response, pt hesitant about SGAs and asked to reconsider antidepressants, but I can't locate any very specific discussion about risk of recurrence with various options, just vague 'avoid class' stuff...
Read more (Source: Student Doctor Network)
Source: Student Doctor Network - March 13, 2022 Category: Universities & Medical Training Authors: Penguin10 Tags: Psychiatry Source Type: forums
Hippocampal avoidance
Randomized phase III evidence shows us this is superior to conventional WBRT. Is this standard of care now? What has been the experience with insurers for those who have been doing this already?
Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. - PubMed - NCBI (Source: Student Doctor Network)
Source: Student Doctor Network - February 23, 2020 Category: Universities & Medical Training Authors: Pointless Tags: Radiation Oncology Source Type: forums
New Meds
There have been several new meds in neurology over the past few years. While many are horrible 'me too,' or the ultimate 'me too' meds: XR versions, poly pills like Aricept+memantine, there has been very real innovation that's helped patients a great deal. I'm thinking of all the new meds in MS: pills, biologics, including ocrelizumab for PPMS. In sleep: orexin antagonist, Belsomra, which I've found very helpful if you set expectations low (it is not a knock-out drug). Seizure management...
New Meds (Source: Student Doctor Network)
Source: Student Doctor Network - October 23, 2019 Category: Universities & Medical Training Authors: neglect Tags: Neurology Source Type: forums
Hippocampal avoidance not (clearly) effective
ASTRO 2018, ~500-person trial (w/ Namenda), "practice changing," cognitive failure reduced by ~8% at 6 mos (~68%->60%), p=0.03
ESTRO 2019, ~160-person trial (? Namenda), at 4 months no difference (p=1.0) and at 8 months ~8% difference (p=0.46)
(Trials w/ p-values in...
Hippocampal avoidance not (clearly) effective (Source: Student Doctor Network)
Source: Student Doctor Network - May 1, 2019 Category: Universities & Medical Training Authors: scarbrtj Tags: Radiation Oncology Source Type: forums
Namenda?
Any experience with Namenda (memantine) in patients with OCD or any of the anxiety disorders? (Source: Student Doctor Network)
Source: Student Doctor Network - May 23, 2016 Category: Universities & Medical Training Authors: cbrons Source Type: forums
