Localized Radiation Therapy or Recombinant Interferon Beta and MSB0010718C With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma
Conditions:   Merkel Cell Polyomavirus Infection;   Stage IV Merkel Cell CarcinomaInterventions:   Drug: Anti-PD-L1 Monoclonal Antibody MSB0010718C;   Radiation: Radiation Therapy;   Biological: Recombinant Interferon Beta;   Biological: MCPyV TAg-specific Polyclonal Autologous CD8-positive T Cells;   Other: Laboratory Biomarker AnalysisSponsors:   Fred Hutchinson Cancer Research Center;   EMD Serono;   National Cancer Institute (NCI)Not yet recruiting - verified October 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 21, 2015 Category: Research Source Type: clinical trials

Localized Radiation Therapy or Recombinant Interferon Beta and Anti-PD-L1 (Avelumab) With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma
Conditions:   Merkel Cell Polyomavirus Infection;   Stage IV Merkel Cell CarcinomaInterventions:   Drug: Anti-PD-L1 Monoclonal Antibody Avelumab;   Radiation: Radiation Therapy;   Biological: Recombinant Interferon Beta;   Biological: MCPyV TAg-specific Polyclonal Autologous CD8-positive T Cells;   Other: Laboratory Biomarker AnalysisSponsors:   Fred Hutchinson Cancer Research Center;   EMD Serono;   National Cancer Institute (NCI)Not yet recruiting - verified October 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 21, 2015 Category: Research Source Type: clinical trials

MLN0128 in Recurrent/Metastatic Merkel Cell Carcinoma
Condition:   Merkel Cell CarcinomaIntervention:   Drug: MLN0128Sponsors:   Dana-Farber Cancer Institute;   Millennium Pharmaceuticals, Inc.Not yet recruiting - verified July 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 28, 2015 Category: Research Source Type: clinical trials