A Study Of SY-3505 Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC
Conditions: Non-small Cell Lung Cancer Interventions: Drug: SY-3505 Capsules; Drug: Crizotinib Capsules Sponsors: Shouyao Holdings (Beijing) Co. LTD Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials

Randomized Clinical Trial of Telenursing for Monitoring Supportive Care Needs in Patients With Lung Cancer and Melanoma Candidates for the First Prescription of Targeted Therapies
Conditions: Lung Neoplasm; Melanoma Interventions: Other: Telenursing interventions for monitoring Supportive Care Needs Sponsors: Regina Elena Cancer Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials

Effectiveness of structured psycho-oncological counseling for relatives of lung cancer patients based on the CALM approach —study protocol of a randomized controlled trial
DiscussionThe study will provide evidence for the effectiveness of the CALM intervention in relatives of lung cancer patients. Furthermore, study results will contribute to a better understanding of the effectiveness of a psycho-oncological intervention for highly impaired cancer patients and their relatives. If the CALM intervention positively affects the relatives ’ psychosocial outcome, it may be implemented in routine care.Trial registrationGerman Clinical Trials Register DRKS00030077. Retrospectively registered on 26 October 2022. (Source: Trials)
Source: Trials - February 10, 2024 Category: Research Source Type: clinical trials

Efficacy and Safety of T-DXd in HER2-mutant Advanced Lung Cancer Patients With Asymptomatic Brain Metastases
Conditions: Non Small Cell Lung Cancer Interventions: Drug: Trastuzumab deruxtecan Sponsors: Yonsei University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens
Conditions: Lung Cancer; Lymph Node Metastasis; Pathologic Processes Interventions: Other: Subjects undergoing a lung specimen lymph node dissection; Other: Control group Sponsors: Brigham and Women ' s Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer
Conditions: Non-small Cell Lung Cancer Stage IB (Resectable); Non-small Cell Lung Cancer Stage II (Resectable); Non-small Cell Lung Cancer Stage ⅢA (Resectable) Interventions: Other: Observational Sponsors: Lawson Health Research Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

Evaluation of Dual Task Performance and Respiratory Muscle Endurance in Patients With Lung Cancer
Conditions: Lung Cancer Interventions: Other: Evaluation of Dual Task Performance Sponsors: Hacettepe University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

Improvement of Quality of Life (QoL) Using Preference-Oriented QoLMonitoring in Patients With Lung Cancer
Conditions: Lung Cancer; Quality of Life Interventions: Behavioral: patient- and physician-centered QoL monitoring; Other: Placebo Sponsors: University of Bayreuth; University of Regensburg, Tumor Center Regensburg, Center for Quality Management and Health Services Research; G-BA Innovationsfonds; University Hospital Regensburg, Center for Clinical Trials; Bavarian Cancer Registry, Bavarian Health and Food Safety Authority, Nuremberg; University Hospital Regensburg; Hospital Barmherzige Br üder Regensburg; Hospital Bayreuth; Hospital Kulmbach; Hospital Coburg; Hospital Bamberg Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials

Efficacy and Safety of Combination Therapy With Bojungikki-tang and Pembrolizumab Monotherapy in Patients With Advanced Non-small Cell Lung Cancer
Conditions: Non-small Cell Lung Cancer Interventions: Drug: Bojungikki-tang(BJIKT); Drug: Pembrolizumab Sponsors: Korea Institute of Oriental Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases
Conditions: Non Small Cell Lung Cancer; NSCLC; KRAS G12C Interventions: Drug: Adagrasib; Radiation: Stereotactic Radiosurgery Sponsors: Ryan Gentzler, MD; Mirati Therapeutics Inc.; University of Virginia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion
Conditions: Non-small Cell Lung Cancer; EGFR Exon 20 Insertion Mutation Interventions: Procedure: Blood sampling Sponsors: Groupe Francais De Pneumo-Cancerologie Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

A Phase IIII Study of AL8326 in Small Cell Lung Cancer
Conditions: Small Cell Lung Carcinoma Interventions: Drug: AL8326 tablets; Drug: placebo Sponsors: Advenchen Laboratories Nanjing Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer
Conditions: Advanced Lung Non-Small Cell Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Stage III Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8 Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Drug: Carfilzomib; Procedure: Computed Tomography; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Sotorasib Sponsors: City of Hope Medical Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.
Conditions: Small Cell Lung Carcinoma Interventions: Radiation: PET based Raditherapy boost Sponsors: University Hospital, Essen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

A Phase 2 Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Patients With Stage 4 Non-Small Cell Lung Cancer
Conditions: NSCLC Interventions: Drug: EIK1001; Biological: Pembrolizumab; Drug: Paclitaxel; Drug: Pemetrexed; Drug: Carboplatin Sponsors: Eikon Therapeutics Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials