Head-to-head Comparison of Positron Nuclide Radio-labeled FAPI and 18F-FDG PET/CT in Patients With Malignant Tumors
Conditions: Renal Cell Carcinoma; Gastric Cancer; Hepatocellular Carcinoma; Signet Ring Cell Carcinoma; Mucinous Adenocarcinoma; Colorectal Cancer Interventions: Diagnostic Test: FAPI PET/CT Sponsors: Guangdong Provincial People ' s Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials

Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors
Conditions: Liver Cancer; Liver Metastases; Liver Metastasis Colon Cancer; Hepatocellular Carcinoma Sponsors: Leiden University Medical Center; Philips Healthcare; European Commission Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 22, 2023 Category: Research Source Type: clinical trials

Clinical Research on Dynamic Monitoring MRD Via Plasma ctDNA After Systemic Therapy of Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma Sponsors: Singlera Genomics Inc.; Shanghai Zhongshan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 21, 2023 Category: Research Source Type: clinical trials

Effects of Cognitive Intervention Therapy on Postoperative Delirium
Conditions: Spinal Stenosis; Disc Herniation; Lung Neoplasms; Carcinoma, Hepatocellular Interventions: Procedure: control group; Procedure: intervention group Sponsors: Yonsei University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 21, 2023 Category: Research Source Type: clinical trials

Influence of Sarcopenia in Hepatocellular Carcinoma Patients
Conditions: Sarcopenia Interventions: Procedure: local ablation; Procedure: TACE; Drug: Sorafenib Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2023 Category: Research Source Type: clinical trials

Radiation Major Hepatectomy to Selectively Treat Unifocal Large Hepatocellular Carcinoma (RESCUE)
Conditions: Hepatocellular Carcinoma Interventions: Procedure: Ablative radioembolization using Yttrium-90 resin microspheres Sponsors: Seoul National University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2023 Category: Research Source Type: clinical trials

Infusional FOLFOX Plus Camrelizumab and Apatinib vs HAIC-FOLFOX Plus Camrelizumab and Apatinib for Advanced HCC
Conditions: BCLC Stage C Hepatocellular Carcinoma; Chemotherapy Effect Interventions: Drug: intravenous FOLFOX7 plus Camrelizumab and apatinib; Drug: HAIC-FOLFOX plus Camrelizumab and apatinib Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials

Role of Abbreviated MRI in Follow-up of Hepatocellular Carcinoma .
Conditions: Hepatocellular Carcinoma Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials

Ablative Radioembolisation for Locally Advanced Hepatocellular Carcinoma (RESOLVE)
Conditions: Hepatocellular Carcinoma Interventions: Procedure: Ablative radioembolization Sponsors: Seoul National University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials

CT Imaging for Guiding PA-TACE for HCC
Conditions: Carcinoma, Hepatocellular Interventions: Procedure: postoperative adjuvant transarterial chemoembolization Sponsors: Zhujiang Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials

Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Longitudinal Monitoring MRD Based on ctDNA
Conditions: Hepatocellular Carcinoma Resectable Interventions: Diagnostic Test: circulating tumor DNA Sponsors: Zhujiang Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials

The effect of switch therapy to tenofovir versus entecavir maintenance on recurrence of hepatocellular carcinoma after surgery (SWITE): study protocol for a randomized controlled trial
AbstractBackgroundAntiviral therapy has been reported to be associated with lower recurrence rate of hepatocellular carcinoma (HCC) for patients with hepatitis B virus (HBV) infection. While entecavir (ETV) and tenofovir disoproxil fumarate (TDF) were both recommended as first-line therapies for HBV patients, recent retrospective studies proposed a lower incidence rate of HCC occurrence or recurrence in those receiving TDF compared ETV. However, the survival benefits of switching to TDF therapy after prolonged ETV treatment before surgery remain uncertain. We delineate the rationale and design of SWITE, a randomized, open-...
Source: Trials - December 2, 2023 Category: Research Source Type: clinical trials

Preoperative dexamethasone administration in hepatectomy of 25-min intermittent Pringle ’s maneuver for hepatocellular carcinoma: protocol for a randomized controlled trial
DiscussionBased on our previous study, we will explore further the effect of glucocorticoid administration on attenuating the surgical stress response in order to follow securely 25-min hepatic inflow occlusion. Therefore, the trial protocol is reasonable and the results of the trial may be clinically significant.Trial registrationThis trial was registered on 3 December 2022, in the Chinese Clinical Trial Registry (http://www.chictr.org.cn), ChiCTR2200066381. The protocol version is V1.0 (20221104). (Source: Trials)
Source: Trials - November 30, 2023 Category: Research Source Type: clinical trials

A Study of [68Ga]Ga-NOTA-RG2 PET Imaging in the Diagnosis of Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma Interventions: Radiation: [68Ga]Ga-NOTA-RG2 PET Imaging Sponsors: Huashan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials

GPC3-directed CAR-T in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma
Conditions: Liver Carcinoma; Hepatic Cell Carcinoma Interventions: Biological: CAR-GPC3 T cells Sponsors: Shanghai Ming Ju Biotechnology Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials