VIBRA trial – Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho
DiscussionThe VIBRA trial is among the first to evaluate the delivery of ART by VHWs immediately after ART initiation. It assesses the entire HIV care cascade from testing to viral suppression. As most countries in sub-Saharan Africa have cadres like the VHW program in Lesotho, this model —if shown to be effective—has the potential to be scaled up. The system impact evaluation will provide valuable cost estimations, and the qualitative research will suggest how the model could be further modified to optimize its impact.Trial registrationClinicaltrials.gov,NCT03630549. Registered on 15 August 2018. (Source: Trials)
Source: Trials - August 21, 2019 Category: Research Source Type: clinical trials
The HOSENG trial – Effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho
DiscussionThe HOSENG trial tests whether oral HIVST may be an add-on during door-to-door testing campaigns towards achieving optimal testing coverage. The provision of oral self-test kits, followed up by VHWs, requires little additional human resources, finances and logistics. If cost-effective, this approach should inform home-based HIV-testing policies not only in Lesotho, but in similar high-prevalence settings.Trial registrationClinicalTrials.gov, (ID:NCT03598686). Registered on 25 July 2018. More information is available atwww.getonproject.wordpress.com. (Source: Trials)
Source: Trials - August 12, 2019 Category: Research Source Type: clinical trials
Peer-Educator-coordinated vs Nurse-coordinated ART Refill for Adolescents and Young Adults Living With HIV in Lesotho
Condition: HIV/AIDS Intervention: Other: PEBRA model Sponsors: Amstutz Alain; International AIDS Society (CIPHER grant); Swiss Tropical & Public Health Institute; SolidarMed; Sentebale; University of Basel; University Hospital, Basel, Switzerland; Swiss National Science Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 31, 2019 Category: Research Source Type: clinical trials
