Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar
Condition: Leprosy Intervention: Drug: Rifampicin Sponsors: Institute of Tropical Medicine, Belgium; Damien Foundation; Centre d’Infectiologie Charles Mérieux; Fondation Raoul Follereau; Leiden University Medical Center; L'Institut National de la Santé et de la Recherche Médicale; Genoscreen; Instituto Fernandes F igueira Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 7, 2018 Category: Research Source Type: clinical trials
Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial
This study provides an opportunity to explore a possible treatment option for HIV-infected patients with cryptosporidial diarrhea, who, as of now in Malawi and most of sub-Saharan Africa, do not have a definitive treatment apart from supportive care. The strength of this study lies in it being a randomized, double-blind, placebo-controlled trial. If shown to be effective and safe, the findings will also lay a foundation for a future study of the use of CFZ in children 6 –18 months of age.Trial registrationClinicalTrials.gov,NCT03341767. Registered on 14 November 2017. (Source: Trials)
Source: Trials - August 23, 2018 Category: Research Source Type: clinical trials
Improved Understanding of Ongoing Transmission of Leprosy in the Hyperendemic Comoros (ComLep)
Condition: Leprosy Intervention: Sponsors: Institute of Tropical Medicine, Belgium; Damien Foundation; Programme National de lutte contre la Lèpre et la Tuberculose, Comores; Instituto Oswaldo Cruz; R2STOP Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 16, 2018 Category: Research Source Type: clinical trials