The Business of Diabetes: CVS Caremark's Salvo in Biosimilar Insulin for 2017
Its already mid-2016, and for nearly the past decade, I ' ve been pushing for so-called " biosimilars " or " follow-on biologics " like insulin to be legalized and then introduced in the U.S. (I first investigated this issue back in 2006, and published anarticle on it in January 2007). The reality is that without any form of generic competition, prices continue to rise with absolutely nothing to stop them. In recent years, there have been some hyper-aggressive price-increases from the insulin oligopoly, especially within the last 3 years or so. The reason: they all KNOW that their insulin analog patents are about...
Source: Scott's Web Log - August 5, 2016 Category: Endocrinology Tags: Biosimilar insulin Lantus Lilly Merck Source Type: blogs
ZERO TOLERANCE for hypoglycemia
Wheat elimination starts you powerfully on the path to reversing diabetes. We’ve seen it many times and it continues to develop in people who kiss their bagels, pretzels, and processed foods booby-trapped with wheat and grains goodbye.
But, as diabetics become less diabetic–a process that can occur VERY quickly, often within days of removing all wheat and grain products from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started ...
Source: Wheat Belly Blog - April 2, 2016 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle diabetes glucose gluten grains hypoglycemia insulin Source Type: blogs
MKSAP: 48-year-old woman with type 1 diabetes mellitus
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 48-year-old woman returns for a follow-up visit for management of type 1 diabetes mellitus. She reports doing well since the last visit. Overall, she believes that most of her blood glucose levels are at goal, but is concerned about occasional episodes of hyperglycemia occurring in the morning before breakfast. She eats a bedtime snack every night that is not covered with mealtime insulin. Review of her blood glucose log demonstrates morning fasting blood glucose values from 80 to 190 mg/dL (4.4 to 10.5 mmol/L...
Source: Kevin, M.D. - Medical Weblog - March 26, 2016 Category: Journals (General) Authors: mksap Tags: Conditions Diabetes Endocrinology Source Type: blogs
What medications have you been able to stop on the Wheat Belly lifestyle?
I posed this question on the Wheat Belly Facebook page recently and received an overwhelming response. Here, I share a partial list of the responses: medications people have been able to stop by following the Wheat Belly lifestyle.
Just take a look at this incredible list: these represent medications prescribed by doctors to, in effect, “treat” the consequences of consuming wheat and grains. They prescribe drugs to treat the inflammation, swelling, skin rashes, gastrointestinal irritation, high blood sugars, airway allergy, and other abnormal effects all caused by wheat and grains.
The list includes anti-inf...
Source: Wheat Belly Blog - October 6, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle asthma cholesterol diabetes drugs gluten grains hypertension prescription medication reflux Source Type: blogs
What It's Really Like Using New Basal Insulin Toujeo
News came early in the year about Sanofi's new basal insulin called Toujeo, which is a higher concentration than the long-established Lantus. You may remember hearing rumors about this insulin years ago while it was still in development, when... (Source: Diabetes Mine)
Source: Diabetes Mine - September 9, 2015 Category: Endocrinology Authors: Mike Hoskins Source Type: blogs
Toujeo, a More Concentrated Version of Lantus Is Now Available
(Source: Diabetes Update)
Source: Diabetes Update - June 23, 2015 Category: Endocrinology Source Type: blogs
I lost the wheat, but didn’t lose the weight: Updated version
Yes, it happens: Rid your life of all things wheat and you get relief from acid reflux, joint pain, and high blood sugars . . . but not weight loss.
While most people enjoy rapid and dramatic weight loss with wheat elimination due to the loss of the appetite-stimulating effect of gliadin-derived opiates, the loss of repetitive glucose-insulin provocation of amylopectin A, the reduction of inflammation from the combined effects of gliadin/wheat germ agglutinin/amylopectin A, and reversal of the leptin-blocking effect of wheat germ agglutinin, this doesn’t happen to everybody. Or you lose, say, 20 pounds, only to have...
Source: Wheat Belly Blog - May 7, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle carbohydrates gluten grains insulin low-carb Thyroid Weight Loss whey Source Type: blogs
MKSAP: 38-year-old pregnant woman with hypertension and diabetes
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 38-year-old woman is evaluated during a follow-up visit. She has a history of well-controlled hypertension and type 1 diabetes mellitus. She is at 16 weeks’ gestation with her first pregnancy. Prior to conception she was taking lisinopril, which was discontinued in anticipation of the pregnancy, and labetalol was initiated. Other medications are insulin glargine, insulin lispro, and a prenatal vitamin.
On physical examination, she appears in good health. Blood pressure is 135/80 mm Hg. There is no edema....
Source: Kevin, M.D. - Medical Weblog - April 26, 2015 Category: Journals (General) Authors: mksap Tags: Conditions Diabetes Heart OB/GYN Source Type: blogs
Ask D'Mine: New Basal Insulin Toujeo, New Dosing Math
Welcome back to our weekly diabetes advice column, Ask D'Mine - with your host veteran type 1, diabetes author and educator Wil Dubois. This week, Wil looks at the newest basal insulin to hit the market: Sanofi's Toujeo (aka the Son of Lantus). ... (Source: Diabetes Mine)
Source: Diabetes Mine - April 25, 2015 Category: Endocrinology Authors: Wil Dubois Source Type: blogs
Medline, PubMed, or both?
A question raised in a recent teaching session with MSc students undertaking systematic reviews. Should I search Medline and PubMed?Actually, people don't usually ask the question, but instead tell you that they have searched both, or that someone has recommended they do so, or that they have read a review where the reviewers have searched both.I always say I am not convinced you need to search both. But am I right?I know PubMed includes things that Medline does not:1. Medline indexes some journals (like Science and Nature) selectively, and will not include non biomedical / life science articles. PubMed, ...
Source: Browsing - April 18, 2015 Category: Databases & Libraries Tags: medline pubmed systematic reviews Source Type: blogs
If you have diabetes: NO low blood sugars!
Wheat elimination starts you powerfully on the path to reversing diabetes. We’ve seen it many times and it continues to develop in people who kiss their bagels, pretzels, and processed foods booby-trapped with wheat goodbye.
But, as diabetics become less diabetic–a process that can occur VERY quickly, often within days of removing all wheat products from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started administ...
Source: Wheat Belly Blog - March 28, 2015 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle blood sugar diabetes gluten grains hypoglycemia Source Type: blogs
Type 1 Diabetes Autoimmunity Makes News
Back in 2012, Novo Nordisk made headlines (whether deservedly or not) for establishing a Seattle research center (see the press release at http://prn.to/1OAukdP for more detail) to focus on autoimmunity that is the core reason type 1 diabetes occurs. Truth be told, there were never more than twenty researchers at this facility, although the company did manage to sign such prominent type 1 diabetes immunologists as Matthias von Herrath whose primary work actually takes place in San Diego at the La Jolla Institute for Allergy & Immunology (LIAI), a non-profit research institute founded in 1988 that focuses on the u...
Source: Scott's Web Log - March 26, 2015 Category: Endocrinology Tags: AstraZeneca Autoimmunity Douglas Melton Novo Nordisk Source Type: blogs
