Betel quid chewing leads to the development of unique de novo malignancies in liver transplant recipients, a retrospective single center study in Taiwan
Abstract: Orthotopic liver transplantation (OLT) is the choice of treatment not only for end-stage liver disease and acute liver failure but also for hepatocellular carcinoma (HCC). The development of de novo malignancies after liver transplantation plays an important role in late mortality; the incidence of late mortality has increased owing to improved survival. The incidence of de novo malignancies is 2.3% to 25%, which is 2 to 3 times that of malignancies in the general population. The most commonly reported de novo malignancies in solid organs are skin cancer, Karposi sarcoma, and colon cancer according to the frequen...
Source: Medicine - September 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Facing up to the ongoing challenge of Kaposi's sarcoma
Purpose of reviewKaposi's sarcoma is a mesenchymal tumour caused by infection with human herpesvirus 8, usually in the context of immunodeficiency. The global incidence of Kaposi's sarcoma rose dramatically with the outbreak of HIV and AIDS. Although the introduction of combined antiretroviral therapy (cART) has seen a dramatic decline in Kaposi's sarcoma incidence, it remains a significant burden of morbidity and mortality, especially in sub-Saharan Africa. This review considers the most recent evidence regarding the prevalence, current treatment strategies and future therapies for Kaposi's sarcoma.
Recent findingsIn the ...
Source: Current Opinion in Infectious Diseases - January 3, 2015 Category: Infectious Diseases Tags: HIV INFECTIONS AND AIDS: Edited by David Dockrell Source Type: research
